CDP-paratose 2-epimerase

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is CDP-3,6-dideoxy-D-glucose 2-epimerase. Other names in common use include CDP-paratose epimerase, cytidine diphosphoabequose epimerase, cytidine diphosphodideoxyglucose epimerase, cytidine diphosphoparatose epimerase, and cytidine diphosphate paratose-2-epimerase. It is also incorrectly known as CDP-abequose epimerase, and CDP-D-abequose 2-epimerase. This enzyme participates in starch and sucrose metabolism. It employs one cofactor, NAD+.

References

Matsuhashi S (1966). "Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. II Reversible 2-epimerization of cytidine diphosphate paratose". J. Biol. Chem. 241 (18): 4275–82. PMID 5924649.
Liu HW, Thorson JS (1994). "Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria". Annu. Rev. Microbiol. 48: 223–56. doi:10.1146/annurev.mi.48.100194.001255. PMID 7826006.

Isomerases: Epimerase and racemases (EC 5.1)

5.1.1: Amino acids	Amino-acid racemase: Phenylalanine racemase (ATP-hydrolysing) Serine racemase

5.1.2: Hydroxy acids	Mandelate racemase

5.1.3: Carbohydrates	UDP-glucose 4-epimerase

5.1.99: Other	Methylmalonyl CoA epimerase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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