Carnosine N-methyltransferase
In enzymology, a carnosine N-methyltransferase (EC 2.1.1.22) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + carnosine
S-adenosyl-L-homocysteine + anserine
Thus, the two substrates of this enzyme are S-adenosyl methionine and carnosine, whereas its two products are S-adenosylhomocysteine and anserine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:carnosine N-methyltransferase. This enzyme participates in histidine metabolism.
References
- McManus IR (1962). "Enzymatic synthesis of anserine in skeletal muscle by N-methylation of carnosine". J. Biol. Chem. 237: 1207–1211.
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