Cirsilineol

Cirsilineol
Names

IUPAC name 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,7-dimethoxychromen-4-one
Other names Eupatrin; 4',5-Dihydroxy-3',6,7-trimethoxyflavone
Identifiers
CAS Number	41365-32-6
ChEBI	CHEBI:3718^Y
ChemSpider	142644
Jmol interactive 3D	Image
PubChem	162464
InChI InChI=1S/C18H16O7/c1-22-13-6-9(4-5-10(13)19)12-7-11(20)16-14(25-12)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3 Key: VKOSQMWSWLZQPA-UHFFFAOYSA-N InChI=1S/C18H16O7/c1-22-13-6-9(4-5-10(13)19)12-7-11(20)16-14(25-12)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3 Key: VKOSQMWSWLZQPA-UHFFFAOYSA-N
SMILES COC1=C(C=CC(=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC)OC)O)O
Properties
Chemical formula	C₁₈H₁₆O₇
Molar mass	344.32 gÂ·mol^âˆ’1
Except where otherwise noted, data are given for materials in their standard state (at 25 Â°C [77 Â°F], 100 kPa).
Infobox references

Cirsilineol is a bioactive flavone isolated from Artemisia^[1] and from Teucrium gnaphalodes.^[2]

References

â†‘ Sheng, X; Sun, Y; Yin, Y; Chen, T; Xu, Q (2008). "Cirsilineol inhibits proliferation of cancer cells by inducing apoptosis via mitochondrial pathway". The Journal of pharmacy and pharmacology 60 (11): 1523â€“9. doi:10.1211/jpp/60.11.0014. PMID 18957174.
â†‘ Flavonoid Aglycones and Glycosides from Teucrium gnaphalodes. F. A. T. BarberÃ¡n, M. I. Gil, F. TomÃ¡s, F. Ferreres and A. Arques, J. Nat. Prod., 1985, 48 (5), pages 859â€“860, doi:10.1021/np50041a040

Flavones and their conjugates

Aglycones

Monohydroxyflavone	6-Hydroxyflavone

Dihydroxyflavones	Chrysin 4',7-Dihydroxyflavone 7,8-Dihydroxyflavone

Trihydroxyflavones	Apigenin Baicalein Norwogonin

Tetrahydroxyflavones	Isoscutellarein Luteolin Norartocarpetin Scutellarein

Pentahydroxyflavones	6-Hydroxyluteolin Hypolaetin Tricetin

O-methylated flavones	Acacetin Alnetin Artocarpetin Chrysoeriol Cirsilineol Cirsiliol Cirsimaritin Diosmetin Eupatilin Genkwanin Hispidulin Nepetin Nobiletin Oroxylin A Pratol Salvigenin Sinensetin Tangeritin Techtochrysin Tricin Wogonin Zapotin

Glycosides

of apigenin	Apiin Apigetrin Isovitexin Rhoifolin Saponarin Schaftoside Vicenin-2 Vitexin

of baicalein	Baicalin Tetuin

of hypolaetin	Hypolaetin 8-glucoside Hypolaetin 8-glucuronide

of luteolin	Cynaroside Isoorientin Orientin Veronicastroside Luteolin-7-O-glucuronide

Giraldiin A and B
Nepitrin
Oroxindin
Scutellarin

Acetylated

Artocarpetin A
Artoindonesianin P

Sulfated glycosides

Theograndin I and II

Polymers

Amentoflavone

Drugs

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