Connexin-32 internal ribosome entry site
| Connexin-32 internal ribosome entry site (IRES) | |
|---|---|
 | |
| Predicted secondary structure and sequence conservation of IRES_Cx32 | |
| Identifiers | |
| Symbol | IRES_Cx32 |
| Rfam | RF00484 |
| Other data | |
| RNA type | Cis-reg; IRES |
| Domain(s) | Eukaryota |
| GO | 0043022 |
| SO | 0000243 |
The connexin-32 internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of connexin 32 and allows cap-independent translation. This internal ribosome entry site (IRES) allows cap independent translation during conditions such as heat shock and stress.[1]
References
- ↑ Hudder, A; Werner R (2000). "Analysis of a Charcot-Marie-Tooth disease mutation reveals an essential internal ribosome entry site element in the connexin-32 gene". J Biol Chem 275 (44): 34586–34591. doi:10.1074/jbc.M005199200. PMID 10931843.
External links
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