Connexin-43 internal ribosome entry site

Connexin-43 internal ribosome entry site (IRES)
Predicted secondary structure and sequence conservation of IRES_Cx43
Identifiers
Symbol IRES_Cx43
Rfam RF00487
Other data
RNA type Cis-reg; IRES
Domain(s) Eukaryota
GO 0043022
SO 0000243

The connexin-43 internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of connexin-43 and allows cap-independent translation. The connexin-43 internal ribosome entry site (IRES) allows cap independent translation during conditions such as heat shock and stress.[1]

References

  1. Schiavi, A; Hudder A; Werner R (1999). "Connexin43 mRNA contains a functional internal ribosome entry site". FEBS Lett 464 (3): 118122. doi:10.1016/S0014-5793(99)01699-3. PMID 10618489.

External links

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