Corydalis ambigua
| Corydalis ambigua | |
|---|---|
 | |
| Scientific classification | |
| Kingdom: | Plantae |
| (unranked): | Angiosperms |
| (unranked): | Eudicots |
| Order: | Ranunculales |
| Family: | Papaveraceae |
| Genus: | Corydalis |
| Species: | C. ambigua |
| Binomial name | |
| Corydalis ambigua Cham. & Schltdl.[1] | |
Corydalis ambigua is a tuberous early flowering east Asian flowering plant species. Its exact native range is obscure due to taxonomic confusion.[1] It is one of the sources of the drug tetrahydropalmatine.
Chemistry
Corydalis ambigua contains a variety of alkaloids including corynoline, acetylcorynoline d-corydalin, dl-tetrahydropalmatine, protopine, tetrahydrocoptisine, dl-tetrahydrocoptisine, d-corybulbine and allo-crytopine.[2][3][4][5]
Chemical derivatives of tetrahydroprotoberberines present in Corydalis ambigua have been studied as potential ways to increase pain tolerance and for treating drug addiction.[6] Further, they may represent a category of neurotransmitter stabilizers which have potential use in broad range of psychotic and neurological disorders.[6]
See also
References
- 1 2 "Corydalis ambigua information from NPGS/GRIN". USDA. 28 Nov 2001. Retrieved 2008-02-04.
- ↑ Zhu, Da-Yuan; et al. (1981). "IDENTIFICATION OF THE STRUCTURES OF CORYDALIS F, I, J AND K". Acta Chimica Sinica.
- ↑ Ma, W.g.; Fukushi, Y.; Tahara, S. (1999). "Fungitoxic alkaloids from Hokkaido Corydalis species". Fitoterapia 70 (3): 258–265. doi:10.1016/S0367-326X(99)00045-3.
- ↑ Hiraoka, Noboru; et al. (2004). "Alkaloid production by somatic embryo cultures of Corydalis ambigua" (PDF). Plant Biotechnology 21 (5): 361–366. doi:10.5511/plantbiotechnology.21.361.
- ↑ Zhu, Xing-Zu (1991). "Memórias do Instituto Oswaldo Cruz - Development of natural products as drugs acting on central nervous system". Memórias do Instituto Oswaldo Cruz 86: 173. doi:10.1590/S0074-02761991000600039.
- 1 2 Zhen X.-C. (2010). "Tetrahydroprotoberberines (THPBs) in neuropsychological disorders: Recent development and prospective (Abstract S-33.004)". International Journal of Neuropsychopharmacology 13 (SUPPL. 1): 41.
Further reading
- Bhakuni, D. S.; Chaturvedi, Rekha (1983). "The Alkaloids of Corydalis meifolia". Journal of Natural Products 46 (4): 466–70. doi:10.1021/np50028a006. PMID 6631434.