Cyclandelate

Cyclandelate
Systematic (IUPAC) name

3,3,5-trimethylcyclohexyl hydroxy(phenyl)acetate
Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Identifiers
CAS Number	456-59-7
ATC code	C04AX01 (WHO)
PubChem	CID 2893
DrugBank	DB04838^Y
ChemSpider	2790^Y
UNII	4139O1OAY2^Y
KEGG	D00286^Y
ChEBI	CHEBI:3988^Y
ChEMBL	CHEMBL1480987
Chemical data
Formula	C₁₇H₂₄O₃
Molar mass	276.37066 g/mol
SMILES O=C(OC1CC(CC(C1)(C)C)C)C(O)c2ccccc2
InChI InChI=1S/C17H24O3/c1-12-9-14(11-17(2,3)10-12)20-16(19)15(18)13-7-5-4-6-8-13/h4-8,12,14-15,18H,9-11H2,1-3H3^Y Key:WZHCOOQXZCIUNC-UHFFFAOYSA-N^Y
Physical data
Melting point	55 to 56.5 °C (131.0 to 133.7 °F)
Boiling point	192 to 194 °C (378 to 381 °F) (14 mmHg)
(verify)

Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis and Raynaud's disease. It is also used to treat nighttime leg cramps, and has been investigated for its effect against migraine. It is orally administered.

References

Peripheral vasodilators (C04)

Phenylethanolamine derivatives	Isoxsuprine Buphenine Bamethan

Imidazoline derivatives Alpha blockers	Phentolamine Tolazoline

Niacin and derivatives	Niacin Nicotinyl alcohol Inositol nicotinate Ciclonicate

Purine derivatives	Pentifylline Xantinol nicotinate Pentoxifylline Etofylline nicotinate

Ergot alkaloids	Ergoloid Nicergoline Dihydroergocristine

Other peripheral vasodilators	Cyclandelate Phenoxybenzamine Vincamine Moxisylyte Bencyclane Vinburnine Sulcotidil Buflomedil Naftidrofuryl Butalamine Visnadine Cetiedil Cinepazide Ifenprodil Azapetine Fasudil

This article is issued from Wikipedia - version of the Thursday, April 28, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.