Suloctidil
 | |
| Systematic (IUPAC) name | |
|---|---|
|
1-[4-(isopropylthio)phenyl]-2-(octylamino)propan-1-ol | |
| Identifiers | |
| CAS Number | 54767-75-8 |
| ATC code | C04AX19 |
| PubChem | CID 5354 |
| ChEMBL | CHEMBL588119 |
| Chemical data | |
| Formula | C20H35NOS |
| Molar mass | 337.563 |
| (verify) | |
Suloctidil was a sulfer-containing aminoalcohol that was brought to market in the early 1970s as a vasodilator by Continental Pharma, a Belgian company.[1]:118–121[2]
Continental was bought by Monsanto in 1984, primarily on the promise of sales of suloctidil, which was approved in Europe at the time, but not in the US.[3] However, in 1985 Monsanto halted development and withdrew the drug worldwide following reports of liver toxicity.[4]:251
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References
- ↑ Josef Hladovec. Antithrombotic Drugs in Thrombosis Models. CRC Press, 1989 ISBN 9780849351624
- ↑ Roncucci R et al. Potential antilipolytic activity of suloctidil. Naturwissenschaften. 1975 Mar;62(3):141-2 PMID 1240601. Paper cites Belgian patent 739678
- ↑ Staff, The Pink Sheet. No vember 5 1984 Monsanto's $150 mil. Life Sciences Research Center
- ↑ Department of Economic and Social Affairs of the United Nations Secretariat Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Twelfth Issue: Pharmaceuticals United Nations – New York, 2005
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