DTDP-L-rhamnose 4-epimerase

DTDP-L-rhamnose 4-epimerase (EC 5.1.3.25, dTDP-4-L-rhamnose 4-epimerase, wbiB (gene)) is an enzyme with systematic name dTDP-6-deoxy-beta-L-talose 4-epimerase.^[1] This enzyme catalyses the following chemical reaction

dTDP-6-deoxy-beta-L-talose

\rightleftharpoons

dTDP-6-deoxy-beta-L-mannose

The equilibrium is strongly towards dTDP-6-deoxy-beta-L-mannose.

References

↑ Yoo, H.G., Kwon, S.Y., Karki, S. and Kwon, H.J. (2011). "A new route to dTDP-6-deoxy-L-talose and dTDP-L-rhamnose: dTDP-L-rhamnose 4-epimerase in Burkholderia thailandensis". Bioorg. Med. Chem. Lett. 21: 3914–3917. doi:10.1016/j.bmcl.2011.05.030. PMID 21640586.

External links

DTDP-L-rhamnose 4-epimerase at the US National Library of Medicine Medical Subject Headings (MeSH)

Isomerases: Epimerase and racemases (EC 5.1)

5.1.1: Amino acids	Amino-acid racemase: Phenylalanine racemase (ATP-hydrolysing) Serine racemase

5.1.2: Hydroxy acids	Mandelate racemase

5.1.3: Carbohydrates	UDP-glucose 4-epimerase

5.1.99: Other	Methylmalonyl CoA epimerase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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