Deoxyinosine monophosphate

Deoxyinosine monophosphate
Names

IUPAC name 2’-Deoxy-5’-inosinic acid
Identifiers
ChEBI	CHEBI:28806
ChemSpider	82650
Jmol interactive 3D	Image
PubChem	91531
InChI InChI=1S/C10H13N4O7P/c15-5-1-7(21-6(5)2-20-22(17,18)19)14-4-13-8-9(14)11-3-12-10(8)16/h3-7,15H,1-2H2,(H,11,12,16)(H2,17,18,19)/t5-,6+,7+/m0/s1 Key: PHNGFPPXDJJADG-RRKCRQDMSA-N InChI=1/C10H13N4O7P/c15-5-1-7(21-6(5)2-20-22(17,18)19)14-4-13-8-9(14)11-3-12-10(8)16/h3-7,15H,1-2H2,(H,11,12,16)(H2,17,18,19)/t5-,6+,7+/m0/s1 Key: PHNGFPPXDJJADG-RRKCRQDMBF
SMILES O=C3/N=C\Nc1c3ncn1[C@@H]2O[C@@H]([C@@H](O)C2)COP(=O)(O)O
Properties
Chemical formula	C₁₀H₁₃N₄O₇P
Molar mass	332.21 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Deoxyinosine monophosphate (dIMP) is a nucleotide monophosphate and a derivative of inosinic acid. It can be formed by the deamination of the purine base in deoxyadenosine monophosphate (dAMP). The enzyme deoxyribonucleoside triphosphate pyrophosphohydrolase, encoded by YJR069C in S. cerevisiae and containing (d)ITPase and (d)XTPase activities, hydrolyses dITP releasing pyrophosphate and dIMP.^[1]

References

↑ Davies O, Mendes P, Smallbone K, Malys N (2012). "Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism". BMB Reports 45 (4): 259–64. doi:10.5483/BMBRep.2012.45.4.259. PMID 22531138.