Dextranomer
Systematic (IUPAC) name | |
---|---|
Dextran, 2,3-dihydroxypropyl 2-hydroxy-1,3-propanediyl ethers | |
Clinical data | |
Trade names | Debrisan |
AHFS/Drugs.com | International Drug Names |
Routes of administration | Topical |
Identifiers | |
CAS Number | 56087-11-7 |
ATC code | D03AX02 |
PubChem | SID 214362 |
ChemSpider | none |
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Dextranomer (trade name Debrisan) is a cicatrizant used in dressings for wound healing,[1] and in pharmaceutical products to treat fecal incontinence.[2] It consists of dextran polymer chains cross-linked into a three-dimensional network.[3]
Solesta
Solesta is the marketed brand name of a system of injections of dextranomer in stabilized sodium hyaluronate for use in fecal incontinence (FI).[4] This preparation is a biocompatible gel, for use as a perianal injectable bulking agent. The system is intended to be injected in the submucosal layer of the proximal anal canal (i.e. above the level of the dentate line).
References
- ↑ Parulkar BG, Sobti MK, Pardanani DS (1985). "Dextranomer dressing in the treatment of infected wounds and cutaneous ulcers". J Postgrad Med 31 (1): 28–33.
- ↑ Solesta Gel Approved for Fecal Incontinence
- ↑ Solesta Package Insert
- ↑ Hoy, SM (Aug 20, 2012). "Dextranomer in stabilized sodium hyaluronate (Solesta): in adults with faecal incontinence.". Drugs 72 (12): 1671–8. doi:10.2165/11209030-000000000-00000. PMID 22845415.
External links
- dextranomer at the US National Library of Medicine Medical Subject Headings (MeSH)
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