(S,S)-butanediol dehydrogenase
(S,S)-butanediol dehydrogenase | |||||||||
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Identifiers | |||||||||
EC number | 1.1.1.76 | ||||||||
CAS number | 37250-14-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a (S,S)-butanediol dehydrogenase (EC 1.1.1.76) is an enzyme that catalyzes the chemical reaction
- (S,S)-butane-2,3-diol + NAD+ acetoin + NADH + H+
Thus, the two substrates of this enzyme are (S,S)-butane-2,3-diol and NAD+, whereas its 3 products are acetoin, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S,S)-butane-2,3-diol:NAD+ oxidoreductase. Other names in common use include L-butanediol dehydrogenase, L-BDH, and L(+)-2,3-butanediol dehydrogenase (L-acetoin forming). This enzyme participates in butanoic acid metabolism.
References
- Taylor MB and Juni E (1960). "Stereoisomeric specificities of 2,3-butanediol dehydrogenase". Biochim. Biophys. Acta 39 (3): 448–457. doi:10.1016/0006-3002(60)90197-9. PMID 13837186.
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