ERC2 (gene)
| ELKS/RAB6-interacting/CAST family member 2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | ERC2 ; CAST; CAST1; ELKSL; SPBC110; Spc110 | ||||||||||||
| External IDs | MGI: 1098749 HomoloGene: 69188 GeneCards: ERC2 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 26059 | 238988 | |||||||||||
| Ensembl | ENSG00000187672 | ENSMUSG00000040640 | |||||||||||
| UniProt | O15083 | Q6PH08 | |||||||||||
| RefSeq (mRNA) | NM_015576 | NM_177814 | |||||||||||
| RefSeq (protein) | NP_056391 | NP_808482 | |||||||||||
| Location (UCSC) |
Chr 3: 55.51 – 56.47 Mb |
Chr 14: 27.62 – 28.48 Mb | |||||||||||
| PubMed search | |||||||||||||
ERC protein 2 is a protein that in humans is encoded by the ERC2 gene.[1]
Interactions
ERC2 (gene) has been shown to interact with PPFIA4,[2] RIMS1[3][4], UNC13A,[5] and liprin-alpha-1.[2]
References
- ↑ "Entrez Gene: ERC2 ELKS/RAB6-interacting/CAST family member 2".
- 1 2 Ko J, Na M, Kim S, Lee JR, Kim E (Oct 2003). "Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins". The Journal of Biological Chemistry 278 (43): 42377–85. doi:10.1074/jbc.M307561200. PMID 12923177.
- ↑ Takao-Rikitsu E, Mochida S, Inoue E, Deguchi-Tawarada M, Inoue M, Ohtsuka T, Takai Y (Jan 2004). "Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release". The Journal of Cell Biology 164 (2): 301–11. doi:10.1083/jcb.200307101. PMC 2172332. PMID 14734538.
- ↑ Ohtsuka T, Takao-Rikitsu E, Inoue E, Inoue M, Takeuchi M, Matsubara K, Deguchi-Tawarada M, Satoh K, Morimoto K, Nakanishi H, Takai Y (Aug 2002). "Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1". The Journal of Cell Biology 158 (3): 577–90. doi:10.1083/jcb.200202083. PMC 2173811. PMID 12163476.
- ↑ "Protein unc-13 homolog A". UniProt.
Further reading
- Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (Jun 2002). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Research : An International Journal for Rapid Publication of Reports on Genes and Genomes 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954. Check date values in:
|year= / |date= mismatch(help) - Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research : An International Journal for Rapid Publication of Reports on Genes and Genomes 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.
- Ohtsuka T, Takao-Rikitsu E, Inoue E, Inoue M, Takeuchi M, Matsubara K, Deguchi-Tawarada M, Satoh K, Morimoto K, Nakanishi H, Takai Y (Aug 2002). "Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1". The Journal of Cell Biology 158 (3): 577–90. doi:10.1083/jcb.200202083. PMC 2173811. PMID 12163476.
- Wang Y, Liu X, Biederer T, Südhof TC (Oct 2002). "A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones". Proceedings of the National Academy of Sciences of the United States of America 99 (22): 14464–9. doi:10.1073/pnas.182532999. PMC 137906. PMID 12391317.
- Ko J, Na M, Kim S, Lee JR, Kim E (Oct 2003). "Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins". The Journal of Biological Chemistry 278 (43): 42377–85. doi:10.1074/jbc.M307561200. PMID 12923177. Check date values in:
|year= / |date= mismatch(help) - Deguchi-Tawarada M, Inoue E, Takao-Rikitsu E, Inoue M, Ohtsuka T, Takai Y (Jan 2004). "CAST2: identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CAST". Genes to Cells : Devoted to Molecular & Cellular Mechanisms 9 (1): 15–23. doi:10.1111/j.1356-9597.2004.00697.x. PMID 14723704.
- Takao-Rikitsu E, Mochida S, Inoue E, Deguchi-Tawarada M, Inoue M, Ohtsuka T, Takai Y (Jan 2004). "Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release". The Journal of Cell Biology 164 (2): 301–11. doi:10.1083/jcb.200307101. PMC 2172332. PMID 14734538.
- tom Dieck S, Altrock WD, Kessels MM, Qualmann B, Regus H, Brauner D, Fejtová A, Bracko O, Gundelfinger ED, Brandstätter JH (Feb 2005). "Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex". The Journal of Cell Biology 168 (5): 825–36. doi:10.1083/jcb.200408157. PMC 2171818. PMID 15728193.
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