Eugenol synthase

Eugenol synthase
Identifiers
EC number	1.1.1.318
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Eugenol synthase (EC 1.1.1.318, LtCES1, EGS1, EGS2) is an enzyme with systematic name eugenol:NADP⁺ oxidoreductase (coniferyl ester reducing).^{[1][2][3][4][5][6]} This enzyme catalyses the following chemical reaction: eugenol + a carboxylate + NADP⁺ $\rightleftharpoons$ a coniferyl ester + NADPH + H⁺

The enzyme acts in the reverse direction.

References

1. Koeduka, T., Fridman, E., Gang, D.R., Vassão, D.G., Jackson, B.L., Kish, C.M., Orlova, I., Spassova, S.M., Lewis, N.G., Noel, J.P., Baiga, T.J., Dudareva, N. and Pichersky, E. (2006). "Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester". Proc. Natl. Acad. Sci. USA 103 (26): 10128–10133. doi:10.1073/pnas.0603732103. PMC 1502517. PMID 16782809.
2. Vassão, D.G., Kim, S.J., Milhollan, J.K., Eichinger, D., Davin, L.B. and Lewis, N.G. (2007). "A pinoresinol-lariciresinol reductase homologue from the creosote bush (Larrea tridentata) catalyzes the efficient in vitro conversion of p-coumaryl/coniferyl alcohol esters into the allylphenols chavicol/eugenol, but not the propenylphenols p-anol/isoeugenol". Arch. Biochem. Biophys. 465 (1): 209–218. doi:10.1016/j.abb.2007.06.002. PMID 17624297.
3. Louie, G.V., Baiga, T.J., Bowman, M.E., Koeduka, T., Taylor, J.H., Spassova, S.M., Pichersky, E. and Noel, J.P. (2007). "Structure and reaction mechanism of basil eugenol synthase". PLoS ONE 2 (10): e993–. doi:10.1371/journal.pone.0000993. PMC 1991597. PMID 17912370.
4. Koeduka, T., Louie, G.V., Orlova, I., Kish, C.M., Ibdah, M., Wilkerson, C.G., Bowman, M.E., Baiga, T.J., Noel, J.P., Dudareva, N. and Pichersky, E. (2008). "The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages". Plant J. 54 (3): 362–374. doi:10.1111/j.1365-313X.2008.03412.x. PMC 2741023. PMID 18208524.
5. Koeduka, T., Baiga, T.J., Noel, J.P. and Pichersky, E. (2009). "Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C₇-C₈ propenyl side chain". Plant Physiol. 149 (1): 384–394. doi:10.1104/pp.108.128066. PMC 2613694. PMID 18987218.
6. Gupta A. K., Schauvinhold I., Pichersky E., and Schiestl F. P. (2014). "Eugenol synthase genes in floral scent variation in Gymnadenia species". Functional & Integrative Genomics. 14 (4): 779–788. doi:10.1007/s10142-014-0397-9.

External links

• Eugenol synthase at the US National Library of Medicine Medical Subject Headings (MeSH)