Extrachromosomal rDNA circle

Extrachromosomal rDNA circles (ERC) are self replicating circles of ribosomal DNA found in some strains of yeast and thought to contribute to their aging.[1] [2] [3]

The ERC accumulate in the mother cell during the budding process.[3]

They are a type of Extrachromosomal Circular DNA (eccDNA),[4] a type of Extrachromosomal DNA.

See also

References

  1. ↑ Sinclair DA, Guarente L (1997). "Extrachromosomal rDNA circles--a cause of aging in yeast." 91 (7): 1033–42. doi:10.1016/S0092-8674(00)80493-6. PMID 9428525.
  2. ↑ "Molecular Mechanisms of Yeast Lifespan Extension by Calorie Restriction". Dec 2007.
  3. 1 2 Nyström (2007). "A Bacterial Kind of Aging".
  4. ↑ Cohen at al. (2003). "Extrachromosomal Circular DNA of Tandemly Repeated Genomic Sequences in Drosophila".


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