FXYD6
| FXYD domain containing ion transport regulator 6 | |
|---|---|
| Identifiers | |
| Symbol | FXYD6 |
| Entrez | 53826 |
| HUGO | 4030 |
| OMIM | 606683 |
| RefSeq | NM_022003 |
| UniProt | Q9H0Q3 |
| Other data | |
| Locus | Chr. 11 q23.3 |
FXYD6 (pronounced fix-id six), or FXYD domain-containing ion transport regulator 6, is a gene which is located at the 11q23.3 (chromosome 11 locus 23.3). The FXYD6 protein contains 95 amino acids, and can be found in all human tissues except blood.
This gene belongs to the FXYD family of ion transport regulators [1]
Pathology
According to recent research, mutations in the FXYD6 gene, or in sequences close by this gene, can predispose to the schizophrenia which is known to be strongly heritable.[2][3]
References
- ↑ ATP1G1/PLM/MAT8 family in PFAM
- ↑ Getting Crowded on Chromosome 11q22—Make Way for Phosphohippolin
- ↑ Choudhury K, McQuillin A, Puri V; et al. (2007). "A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia". Am. J. Hum. Genet. 80 (4): 664–72. doi:10.1086/513475. PMC 1852702. PMID 17357072.
External links
This article is issued from Wikipedia - version of the Monday, June 08, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.