Ferredoxin—nitrate reductase

ferredoxin—nitrate reductase
Identifiers
EC number	1.7.7.2
CAS number	60382-69-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a ferredoxin—nitrate reductase (EC 1.7.7.2) is an enzyme that catalyzes the chemical reaction

nitrite + H₂O + 2 oxidized ferredoxin $\rightleftharpoons$ nitrate + 2 reduced ferredoxin + 2 H⁺

The 3 substrates of this enzyme are nitrite, H₂O, and oxidized ferredoxin, whereas its 3 products are nitrate, reduced ferredoxin, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is nitrite:ferredoxin oxidoreductase. Other names in common use include assimilatory nitrate reductase, nitrate (ferredoxin) reductase, and assimilatory ferredoxin-nitrate reductase. This enzyme participates in nitrogen metabolism. It has 4 cofactors: iron, Sulfur, Molybdenum, and Iron-sulfur.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1PFD.

References

• Mikami B and Ida S (1984). "Purification and properties of ferrodoxin-nitrate reductase from the cyanobacterium Plectonema borganum". Biochim. Biophys. Acta 791: 294–304. doi:10.1016/0167-4838(84)90340-6.