Ferric-chelate reductase (NADPH)

Identifiers

Databases

IntEnz

IntEnz view

PDB structures

Search
PMC	articles
PubMed	articles
NCBI	proteins

Ferric-chelate reductase (NADPH) (EC 1.16.1.9, ferric chelate reductase, iron chelate reductase, NADPH:Fe³⁺-EDTA reductase, NADPH-dependent ferric reductase, yqjH (gene)) is an enzyme with systematic name Fe(II):NADP⁺ oxidoreductase.^[1]^[2]^[3] This enzyme catalyses the following chemical reaction

2 Fe(II) + 2 apo-siderophore + NADP⁺ + H⁺

\rightleftharpoons

2 Fe(III)-siderophore + NADPH

Ferric-chelate reductase contains FAD.

References

↑ Bamford, V.A., Armour, M., Mitchell, S.A., Cartron, M., Andrews, S.C. and Watson, K.A. (2008). "Preliminary X-ray diffraction analysis of YqjH from Escherichia coli: a putative cytoplasmic ferri-siderophore reductase". Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64 (Pt 9): 792–796. doi:10.1107/S174430910802352X. PMC 2531270. PMID 18765906.
↑ Wang, S., Wu, Y. and Outten, F.W. (2011). "Fur and the novel regulator YqjI control transcription of the ferric reductase gene yqjH in Escherichia coli". J. Bacteriol. 193 (2): 563–574. doi:10.1128/JB.01062-10. PMC 3019823. PMID 21097627.
↑ Miethke, M., Hou, J. and Marahiel, M.A. (2011). "The Siderophore-Interacting Protein YqjH Acts as a Ferric Reductase in Different Iron Assimilation Pathways of Escherichia coli". Biochemistry 50 (50): –. doi:10.1021/bi201517h. PMID 22098718.

External links

Ferric-chelate reductase (NADPH) at the US National Library of Medicine Medical Subject Headings (MeSH)

Other oxidoreductases (EC 1.15-1.21)

1.15: Acting on superoxide as acceptor	Superoxide dismutase SOD1 SOD2 SOD3

1.16: Oxidizing metal ions	Ceruloplasmin

1.17: Acting on CH or CH2 groups	Xanthine oxidase Ribonucleotide reductase 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase

1.18: Acting on iron-sulfur proteins as donors	Nitrogenase

1.19: Acting on reduced flavodoxin as donor	Nitrogenase (flavodoxin)

1.20: Acting on phosphorus or arsenic in donors	Glutaredoxin GLRX GLRX2 GLRX3 GLRX5

1.21: Acting on X-H and Y-H to form an X-Y bond	Isopenicillin N synthase Columbamine oxidase Reticuline oxidase Sulochrin oxidase (+)-bisdechlorogeodin-forming (-)-bisdechlorogeodin-forming Aureusidin synthase Tetrahydrocannabinolic acid synthase Cannabidiolic acid synthase Dichlorochromopyrrolate synthase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

This article is issued from Wikipedia - version of the Thursday, March 31, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.

Ferric-chelate reductase (NADPH)

References

See also

External links