Filenadol

Filenadol
Systematic (IUPAC) name

(1R,2S)-1-(1,3-benzodioxol-5-yl)-1-(4-morpholinyl)-2-propanol
Identifiers
CAS Number	78168-92-0^Y
ATC code	None
PubChem	CID 71224
ChemSpider	64359^N
ChEMBL	CHEMBL2104364
Synonyms	(±)-erythro-1-(3,4-methylenedioxyphenyl)-1-morpholinopropan-2-ol
Chemical data
Formula	C₁₄H₁₉NO₄
Molar mass	265.305 g/mol
SMILES O[C@H]([C@H](N1CCOCC1)c3ccc2OCOc2c3)C
InChI InChI=1S/C14H19NO4/c1-10(16)14(15-4-6-17-7-5-15)11-2-3-12-13(8-11)19-9-18-12/h2-3,8,10,14,16H,4-7,9H2,1H3/t10-,14-/m0/s1^N Key:KFSXLIJSXOJBCB-HZMBPMFUSA-N^N
^NY (what is this?) (verify)

Filenadol (INN; Filantor; FI-2024) is an analgesic drug with antinociceptive and antiinflammatory properties.^[1]^[2]

References

↑ F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 890. ISBN 978-0-412-46630-4. Retrieved 15 May 2012.
↑ Bustos G, Ferrándiz ML, Sanz MJ, Payá M, Alcaraz MJ (1995). "Antinociceptive activity of filenadol on inflammatory pain". Life Sciences 57 (14): PL181–6. doi:10.1016/0024-3205(95)02098-4. PMID 7564876.

Analgesics (N02A, N02B)

Opioids

Opiates/opium	Codeine^# Morphine^# Opium Laudanum Paregoric

Semisynthetic	Acetyldihydrocodeine Benzylmorphine Buprenorphine Desomorphine Diacetylmorphine (heroin) Dihydrocodeine Dihydromorphine Ethylmorphine Hydrocodone Hydromorphinol Hydromorphone Nicocodeine Nicodicodeine Nicomorphine Oxycodone /paracetamol Oxymorphone Thebacon

Synthetic	Alphaprodine Anileridine Butorphanol Dextromoramide Dextropropoxyphene Dezocine Fentanyl Ketobemidone Levorphanol Meptazinol Methadone Nalbuphine Pentazocine Pethidine Phenadoxone Phenazocine Piminodine Piritramide Propiram Tapentadol Tilidine Tramadol

Anilines

Acetanilide^‡
Bucetin^‡
Butacetin^‡
Paracetamol (acetaminophen)^#
Parapropamol^‡
Phenacetin^‡
Propacetamol^‡

NSAIDs

Propionates	Fenoprofen Flurbiprofen Ibuprofen^# Ketoprofen Naproxen Oxaprozin

Oxicams	Meloxicam Piroxicam

Acetates	Diclofenac Indometacin Ketorolac Nabumetone Sulindac Tolmetin

COX-2 inhibitors	Celecoxib Etoricoxib Lumiracoxib Parecoxib Rofecoxib ^‡ Valdecoxib ^‡

Fenamates	Meclofenamic acid Mefenamic acid

Salicylates	Aspirin (acetylsalicylic acid)^# (+paracetamol/caffeine) Benorylate Diflunisal Ethenzamide Magnesium salicylate Salicin Salicylamide Salsalate Wintergreen (methyl salicylate)

Pyrazolones	Aminophenazone^‡ Ampyrone Metamizole (dipyrone) Nifenazone Phenazone Propyphenazone

Others	Glafenine

Cannabinoids

Channelergics

Calcium blockers	Gabapentin Gabapentin enacarbil Pregabalin Ziconotide

Sodium blockers	Carbamazepine Lacosamide Local anesthetics (e.g., cocaine, lidocaine) Mexiletine Nefopam Tricyclic antidepressants (e.g., amitriptyline^#)

Potassium openers	Flupirtine

Myorelaxants

Others

Camphor
Capsaicin
Clonidine
Ketamine
Menthol
Methoxyflurane
Nefopam
Proglumide
Tricyclic antidepressants (e.g., amitriptyline^#)

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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