4-Fluoro-L-threonine

4-Fluoro-L-threonine
Names
IUPAC name
(2S,3S)-2-Amino-4-fluoro-3-hydroxybutanoic acid
Other names
4-Fluorothreonine
Identifiers
102130-93-8
ChemSpider 113553
Jmol 3D model Interactive image
PubChem 128057
Properties
C4H8FNO3
Molar mass 137.11 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

4-Fluoro-L-threonine is an antibacterial made by Streptomyces cattleya. It is formed by the fluorothreonine transaldolase catalysed transfer of fluoroacetaldehyde onto threonine.[1]

References

  1. Murphy CD, O'Hagan D, Schaffrath C (2001). "Identification of a PLP-Dependent Threonine Transaldolase: A Novel Enzyme Involved in 4-Fluorothreonine Biosynthesis in Streptomyces cattleya This work was supported by the Biotechnological and Biological Sciences Research Council and the University of St Andrews". Angew. Chem. Int. Ed. Engl. 40 (23): 44794481. doi:10.1002/1521-3773(20011203)40:23<4479::AID-ANIE4479>3.0.CO;2-1. PMID 12404452.


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