Fraxetin

Fraxetin
Names

IUPAC name 7,8-dihydroxy-6-methoxychromen-2-one
Other names 7,8-Dihydroxy-6-methoxycoumarin
Identifiers
CAS Number	574-84-5
ChemSpider	4437972
EC Number	209-376-2
Jmol interactive 3D	Image
KEGG	C09265
PubChem	5273569
InChI InChI=1S/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3 Key: HAVWRBANWNTOJX-UHFFFAOYSA-N InChI=1/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3 Key: HAVWRBANWNTOJX-UHFFFAOYAM
SMILES COC1=C(C(=C2C(=C1)C=CC(=O)O2)O)O
Properties
Chemical formula	C₁₀H₈O₅
Molar mass	208.17 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Fraxetin is an O-methylated coumarin. It can be found in Fraxinus rhynchophylla.^[1] Fraxin is a glucoside of fraxetin.

References

↑ Thuong, PT; Pokharel, YR; Lee, MY; Kim, SK; Bae, K; Su, ND; Oh, WK; Kang, KW (2009). "Dual anti-oxidative effects of fraxetin isolated from Fraxinus rhinchophylla". Biological & Pharmaceutical Bulletin 32 (9): 1527–32. doi:10.1248/bpb.32.1527. PMID 19721227.

Types of coumarins

Aglycones

O-Methylated	Fraxetin Herniarin (7-O-Methylumbelliferone) Osthol Scopoletin (6-Methoxyumbelliferone)

glycosides

Aesculin (Esculetin 6-O-glucoside)
Fraxin (Fraxetin glucoside)
Skimmin (Umbelliferone 7-O-glucoside)
Scopolin
Umbelliferone 7-apiosylglucoside

derivatives

Furanocoumarins

Aglycones

Angelicin
Marmesin
Psoralen
Vaginol
Xanthotoxol (8-Hydroxypsoralen)

O-Methylated	Bergapten (5-methoxypsoralen) Isopimpinellin (5,8-Dimethoxypsoralene) Methoxsalen (8-Methoxypsoralen) Trioxsalen (2,5,9-Trimethylpsoralen)

Furanocoumarin glycosides

Apterin (vaginol glucoside)

Meroterpene furanocoumarin ether

Oligomers

Dicoumarol

Synthetic

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