Fumarylacetoacetic acid

Fumarylacetoacetic acid

Names
IUPAC name (E)-4,6-Dioxooct-2-enedioic acid
Other names Fumarylacetoacetate
Identifiers
CAS Number	28613-33-4
ChemSpider	4444081
Jmol interactive 3D	Image
MeSH	Fumarylacetoacetate
PubChem	5280398
InChI InChI=1S/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1+ Key: GACSIVHAIFQKTC-OWOJBTEDSA-N InChI=1/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1+ Key: GACSIVHAIFQKTC-OWOJBTEDBU
SMILES O=C(\C=C\C(=O)O)CC(=O)CC(=O)O
Properties
Chemical formula	C8H8O6
Molar mass	200.15 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Fumarylacetoacetic acid (fumarylacetoacetate) is an intermediate in the metabolism of tyrosine. It is formed through the conversion of maleylacetoacetate into fumarylacetoacetate by the enzyme maleylacetoacetate isomerase.^[1]

See also

• Fumarylacetoacetate hydrolase

References

1. W. E. Knox and M. LeMay-Knox (1951). "The oxidation in liver of l-tyrosine to acetoacetate through p-hydroxyphenylpyruvate and homogentisic acid". Biochem. J. 49: 686–693.