Fumigaclavine A dimethylallyltransferase

Fumigaclavine A dimethylallyltransferase (EC 2.5.1.100, FgaPT1) is an enzyme with systematic name dimethylallyl-diphosphate:fumigaclavine A dimethylallyltransferase.^[1] This enzyme catalyses the following chemical reaction

fumigaclavine A + dimethylallyl diphosphate

\rightleftharpoons

fumigaclavine C + diphosphate

Fumigaclavine C is an ergot alkaloid produced by some fungi of the Trichocomaceae family.

References

↑ Unsöld, I.A. and Li, S.M. (2006). "Reverse prenyltransferase in the biosynthesis of fumigaclavine C in Aspergillus fumigatus: gene expression, purification, and characterization of fumigaclavine C synthase FGAPT1". ChemBioChem. 7 (1): 158–164. doi:10.1002/cbic.200500318. PMID 16397874.

External links

Fumigaclavine A dimethylallyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)

Transferases: alkyl and aryl (EC 2.5)

2.5.1	Dimethylallyltranstransferase Thiaminase I Methionine adenosyltransferase Riboflavin synthase Dihydropteroate synthase Spermidine synthase Glutathione S-transferase Farnesyl-diphosphate farnesyltransferase Spermine synthase Alkylglycerone phosphate synthase Farnesyltransferase Geranylgeranyltransferase type 1 Porphobilinogen deaminase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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