Guanazodine

Guanazodine
Systematic (IUPAC) name


2-(Azocan-2-ylmethyl)guanidine
Identifiers
CAS Number	32059-15-7
ATC code	C02CC06 (WHO)
PubChem	CID 36054
ChemSpider	33166
UNII	7N05KQ38YI^Y
KEGG	D07169^Y
ChEMBL	CHEMBL2008565
Chemical data
Formula	C₉H₂₀N₄
Molar mass	184.28 g/mol
SMILES C1CCCNC(CC1)CNC(=N)N
InChI InChI=1S/C9H20N4/c10-9(11)13-7-8-5-3-1-2-4-6-12-8/h8,12H,1-7H2,(H4,10,11,13) Key:ZCVAIGPGEINFCX-UHFFFAOYSA-N
(verify)

Guanazodine is a sympatholytic drug.

Sympatholytic (and closely related) antihypertensives (C02)

Sympatholytics
(antagonize α-adrenergic
vasoconstriction)

Central

α₂ agonist	Clonidine Guanabenz Guanfacine Methyldopa^# Tiamenidine^‡

Adrenergic release inhibitors	Bethanidine Bretylium Debrisoquine Guanadrel Guanazodine Guanethidine Guanoclor Guanazodine Guanoxabenz Guanoxan

Imidazoline receptor agonist	Moxonidine Rilmenidine

Ganglion-blocking/nicotinic antagonist	Hexamethonium^‡ Mecamylamine Pentolinium Trimethaphan

Peripheral

Indirect

MAOI	Pargyline^‡

Adrenergic uptake inhibitor	Bietaserpine Deserpidine Methoserpidine Rescinnamine Reserpine

Tyrosine hydroxylase inhibitor	Metirosine

Direct

α₁ blockers	Prazosin Indoramin Trimazosin Doxazosin Urapidil

Non-selective α blocker	Phentolamine

Other antagonists

Serotonin antagonist	Ketanserin Lidanserin

Endothelin antagonist (for PH)	dual (Bosentan, Macitentan) selective (Ambrisentan, Sitaxentan)

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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