Hairy RNA localisation element (HLE)
| Hairy RNA localisation element (HLE) | |
|---|---|
 | |
| Predicted secondary structure and sequence conservation of HLE | |
| Identifiers | |
| Symbol | HLE |
| Rfam | RF00437 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Eukaryota |
| SO | 0000233 |
The hairy localisation element (HLE) is an RNA element found in the 3' UTR of the hairy gene. HLE contains two stem-loops. HLE is essential for the mediation of apical localisation and the two stem-loop structures act to allow the recognition of hairy mRNA by the localisation machinery.[1] HLE is found in Drosophila species.
References
- ↑ Bullock, SL; Zicha D; Ish-Horowicz D (2003). "The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport". EMBO J 22 (10): 2484–2494. doi:10.1093/emboj/cdg230. PMC 155988. PMID 12743042.
External links
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