Hydroxydechloroatrazine ethylaminohydrolase

hydroxydechloroatrazine ethylaminohydrolase
Identifiers
EC number	3.5.99.3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a hydroxydechloroatrazine ethylaminohydrolase (EC 3.5.99.3) is an enzyme that catalyzes the chemical reaction

4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H₂O $\rightleftharpoons$ N-isopropylammelide + ethylamine

Thus, the two substrates of this enzyme are 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine and H₂O, whereas its two products are N-isopropylammelide and ethylamine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in compounds that have not been otherwise categorized within EC number 3.5. The systematic name of this enzyme class is 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase. Other names in common use include AtzB, and hydroxyatrazine ethylaminohydrolase. This enzyme participates in atrazine degradation.

References

• MJ; De Souza, ML; Mandelbaum, RT; Wackett, LP; Sadowsky, MJ (1997). "The atzB gene of Pseudomonas sp. strain ADP encodes the second enzyme of a novel atrazine degradation pathway". Appl. Environ. Microbiol. 63 (3): 916–23. PMC 168384. PMID 9055410.