Indolin-2-one monooxygenase

Indolin-2-one monooxygenase
Identifiers
EC number 1.14.13.138
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Indolin-2-one monooxygenase (EC 1.14.13.138, BX3 (gene), CYP71C2 (gene)) is an enzyme with systematic name indolin-2-one,NAD(P)H:oxygen oxidoreductase (3-hydroxylating).[1][2] This enzyme catalyses the following chemical reaction

indolin-2-one + NAD(P)H + H+ + O2 \rightleftharpoons 3-hydroxyindolin-2-one + NAD(P)+ + H2O

Indolin-2-one monooxygenase is involved in the biosynthesis of protective and allelophatic benzoxazinoids in some plants.

References

  1. Frey, M., Chomet, P., Glawischnig, E., Stettner, C., Grün, S., Winklmair, A., Eisenreich, W., Bacher, A., Meeley, R.B., Briggs, S.P., Simcox, K. and Gierl, A. (1997). "Analysis of a chemical plant defense mechanism in grasses". Science 277 (5326): 696–699. doi:10.1126/science.277.5326.696. PMID 9235894.
  2. Glawischnig, E., Grun, S., Frey, M. and Gierl, A. (1999). "Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses". Phytochemistry 50 (6): 925–930. doi:10.1016/s0031-9422(98)00318-5. PMID 10385992.

External links

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