Isoaminile

Isoaminile
Systematic (IUPAC) name

4-(dimethylamino)-2-isopropyl-2-phenylpentanenitrile
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	77-51-0^Y
ATC code	R05DB04 (WHO)
PubChem	CID 6481
DrugBank	DB08944^N
ChemSpider	6236^Y
UNII	R4823W2PQL^Y
KEGG	D08088^Y
Chemical data
Formula	C₁₆H₂₄N₂
Molar mass	244.375 g/mol
SMILES N#CC(c1ccccc1)(C(C)C)CC(N(C)C)C
InChI InChI=1S/C16H24N2/c1-13(2)16(12-17,11-14(3)18(4)5)15-9-7-6-8-10-15/h6-10,13-14H,11H2,1-5H3^Y Key:WFLSCFISQHLEED-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Isoaminile is an antitussive (cough suppressant) used under the trade-name Peracon.^[1]

The normal therapeutic dose is 40–80 mg of the cyclamate salt, with a maximum of five doses in a 24-hour period. In addition to its central antitussive effects, it is also an anticholinergic, exhibiting both antimuscarinic and antinicotinic actions.

References

↑ Chappel, C. I.; von Seeman, C. (1963). "Antitussive Drugs". In Ellis, G. P.; West, G. B. Progress in Medicinal Chemistry 3. Butterworth. pp. 114–115. doi:10.1016/S0079-6468(08)70117-6. ISBN 978-0-444-53322-7. Retrieved 2013-09-12.

Cough and cold preparations (R05)

Expectorants

Mucolytics

Cough suppressants

Opium alkaloids, opioids, and derivatives	Acetyldihydrocodeine Benzylmorphine Butorphanol Codeine Dextromethorphan Dihydrocodeine Dimemorfan Droxypropine Ethylmorphine Heroin Hydrocodone Hydromorphone Isoaminile Laudanum Levomethadone Levopropoxyphene Methadone Nicocodeine Nicodicodeine Normethadone Noscapine Pholcodine Thebacon Tipepidine

Other	Benzonatate Benproperine Bibenzonium bromide Butamirate Clobutinol Clofedanol Cloperastine Diphenhydramine Dibunate Dimethoxanate Dropropizine Fedrilate Glaucine Levodropropizine Meprotixol Morclofone Nepinalone Oxolamine Oxeladin Pentoxyverine Pipazetate Prenoxdiazine Piperidione Zipeprol

This article is issued from Wikipedia - version of the Saturday, April 02, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.