K10 transport/localisation element (TLS)
| K10 transport/localisation element (TLS) | |
|---|---|
 | |
| Predicted secondary structure and sequence conservation of K10_TLS | |
| Identifiers | |
| Symbol | K10_TLS |
| Rfam | RF00207 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Eukaryota |
| SO | 0005836 |
The K10 transport/localisation element (TLS) is an 44 nucleotide K10 TLS regulatory element from Drosophila melanogaster. K10 TLS is responsible for the transport and anterior localisation of K10 mRNA and acts to establish dorsoventral polarity in the oocyte.[1][2] It was discovered by Julia Serano.
References
- ↑ Serano, TL; Cohen RS (1995). "A small predicted stem-loop structure mediates oocyte localization of Drosophila K10 mRNA". Development 121 (11): 3809–3818. PMID 8582290.
- ↑ Guillemin, K; Williams T; Krasnow MA (2001). "A nuclear lamin is required for cytoplasmic organization and egg polarity in Drosophila". Nat Cell Biol 3 (9): 848–851. doi:10.1038/ncb0901-848. PMID 11533666.
External links
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