L-lactate dehydrogenase (cytochrome)

L-lactate dehydrogenase (cytochrome)

Identifiers

Databases

metabolic pathway

PDB structures

RCSB PDB PDBe PDBsum

Search
PMC	articles
PubMed	articles
NCBI	proteins

In enzymology, an L-lactate dehydrogenase (cytochrome) (EC number 1.1.2.3) is an enzyme that catalyzes the chemical reaction

(S)-lactate + 2 ferricytochrome c

\rightleftharpoons

pyruvate + 2 ferrocytochrome c

Thus, the two substrates of this enzyme are (S)-lactate and ferricytochrome c, whereas its two products are pyruvate and ferrocytochrome c.

References

Further reading

Appleby CA, Morton RK (March 1959). "Lactic dehydrogenase and cytochrome b2 of baker's yeast; purification and crystallization". Biochem. J. 71 (3): 492–9. PMC 1196822. PMID 13638255.
Appleby CA, Morton RK (November 1959). "Lactic dehydrogenase and cytochrome b2 of baker's yeast. Enzymic and chemical properties of the crystalline enzyme". Biochem. J. 73: 539–50. PMC 1197094. PMID 13793977.
Bach SJ, Dixon M, Zerfas LG (1946). "Yeast lactic dehydrogenase and cytochrome b(2)". Biochem. J. 40 (2): 229–39. PMC 1258326. PMID 16747991.

Oxidoreductases: alcohol oxidoreductases (EC 1.1)

1.1.1: NAD/NADP acceptor	3-hydroxyacyl-CoA dehydrogenase 3-hydroxybutyryl-CoA dehydrogenase Alcohol dehydrogenase Aldo-keto reductase 1A1 1B1 1B10 1C1 1C3 1C4 7A2 Aldose reductase Beta-Ketoacyl ACP reductase Carbohydrate dehydrogenases Carnitine dehydrogenase D-malate dehydrogenase (decarboxylating) DXP reductoisomerase Glucose-6-phosphate dehydrogenase Glycerol-3-phosphate dehydrogenase HMG-CoA reductase IMP dehydrogenase Isocitrate dehydrogenase Lactate dehydrogenase L-threonine dehydrogenase L-xylulose reductase Malate dehydrogenase Malate dehydrogenase (decarboxylating) Malate dehydrogenase (NADP+) Malate dehydrogenase (oxaloacetate-decarboxylating) Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) Phosphogluconate dehydrogenase Sorbitol dehydrogenase Hydroxysteroid dehydrogenase: 3 Beta 3-beta-HSD NSDHL 11 Beta HSD11B1 HSD11B2 17 Beta

1.1.2: cytochrome acceptor	D-lactate dehydrogenase (cytochrome) D-lactate dehydrogenase (cytochrome c-553) Mannitol dehydrogenase (cytochrome)

1.1.3: oxygen acceptor	Glucose oxidase L-gulonolactone oxidase Xanthine oxidase

1.1.4: disulfide as acceptor	Vitamin K epoxide reductase Vitamin-K-epoxide reductase (warfarin-insensitive)

1.1.5: quinone/similar acceptor	Malate dehydrogenase (quinone) Quinoprotein glucose dehydrogenase

1.1.99: other acceptors	Choline dehydrogenase L2HGDH

Proteins: enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

This article is issued from Wikipedia - version of the Thursday, December 31, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.