List of steroid abbreviations

The steroid hormones are referred to by various abbreviations in the biological literature. The purpose of this list is to give commonly used abbreviations for steroid hormones, with supporting references to the literature.

Table of abbreviations

Trivial NameAbbreviation(s)Systematic Name
CholesterolChol[1]5-cholesten-3beta-ol
Progestins
PregnenoloneP5[2] or Preg[3]3beta-hydroxy-5-pregnen-20-one
17-hydroxypregnenolone17-OHP5[4] or 17P5[5]3beta,17-dihydroxy-5-pregnen-20-one
ProgesteroneP4[6] or P[3]4-pregnene-3,20-dione
17-hydroxyprogesterone17-OHP4[4] or 17OHP[7] or 17P4[5]17-hydroxy-4-pregnene-3,20-dione
Androgens
AndrostenedioneA4[8] or AE[9]4-androstene-3,17-dione
4-Hydroxyandrostenedione4-OH-A[3]
11β-Hydroxyandrostenedione11βOHA4[10] or 11βOHΔ4[11] or OHA[12]11beta-4-androstene-3,17-dione
AndrostanediolAdiol[13]3-beta,17-beta-Androstanediol
AndrosteroneAN[9]3alpha-hydroxy-5alpha-androstan-17-one
EpiandrosteroneEPIA[14]3beta-hydroxy-5alpha-androstan-17-one
AdrenosteroneAT4-androstene-3,11,17-trione
DehydroepiandrosteroneDHEA[15] or DHA[16]3beta-hydroxy-5-androsten-17-one
Dehydroepiandrosterone sulfate DHEAS[8] or DHAS[16]3beta-sulfooxy-5-androsten-17-one
TestosteroneT[4]17beta-hydroxy-4-androsten-3-one
EpitestosteroneepiT[17]17alpha-hydroxy-4-androsten-3-one
5α-DihydrotestosteroneDHT[15] or 5α-DHT[18]17beta-hydroxy-5alpha-androstan-3-one
5β-Dihydrotestosterone5β-DHT[18]17beta-hydroxy-5beta-androstan-3-one
11β-HydroxytestosteroneOHT[12] or 11β-OHT[19]11beta,17beta-dihydroxy-4-androsten-3-one
11-Ketotestosterone11-KT[20]17beta-hydroxy-4-androsten-3,17-dione
Estrogens
EstroneE1[6]3-hydroxy-1,3,5(10)-estratrien-17-one
EstradiolE2[4]1,3,5(10)-estratriene-3,17beta-diol
EstriolE3[6]1,3,5(10)-estratriene-3,16alpha,17beta-triol
Corticosteroids
CorticosteroneB[7] or CORT[21]11beta,21-dihydroxy-4-pregnene-3,20-dione
DeoxycorticosteroneDOC[7]21-hydroxy-4-pregnene-3,20-dione
CortisolF[7]11beta,17,21-trihydroxy-4-pregnene-3,20-dione
11-DeoxycortisolS[22]17,21-dihydroxy-4-pregnene-3,20-dione
CortisoneE[7]17,21-dihydroxy-4-pregnene-3,11,20-trione
18-Hydroxycorticosterone18OHB[23] or 18B[24]11beta,18,21-trihydroxy-4-pregnene-3,20-dione
1α-Hydroxycorticosterone1α-B[25]1alpha,11beta, 21-trihydroxy-4-pregnene-3,20-dione
AldosteroneA[7] or ALDO[26]18,11-hemiacetal of 11beta,21-dihydroxy-3,20-dioxo-4-pregnen-18-al

References

  1. ↑ Needham D, McIntosh TJ, Evans E (1988). "Thermomechanical and transition properties of dimyristoylphosphatidylcholine/cholesterol bilayers". Biochemistry 27 (13): 4668–73. doi:10.1021/bi00413a013. PMID 3167010.
  2. ↑ Henson MC, Pepe GJ, Albrecht ED (1987). "Transuterofetoplacental conversion of pregnenolone to progesterone in antiestrogen-treated baboons". Endocrinology 121 (4): 1265–71. doi:10.1210/endo-121-4-1265. PMID 3653027.
  3. 1 2 3 Spinola PG, Marchetti B, Mérand Y, Bélanger A, Labrie F (1988). "Effects of the aromatase inhibitor 4-hydroxyandrostenedione and the antiandrogen flutamide on growth and steroid levels in DMBA-induced rat mammary tumors". Breast Cancer Res. Treat. 12 (3): 287–96. doi:10.1007/BF01811241. PMID 3147727.
  4. 1 2 3 4 Martikainen H, Rönnberg L, Ruokonen A, Vihko R (1985). "Testicular responsiveness to hCG before and after long-term antiestrogen treatment in oligozoospermic men". J. Steroid Biochem. 23 (5A): 651–5. doi:10.1016/0022-4731(85)90017-2. PMID 4079381.
  5. 1 2 Miura T, Higuchi M, Ozaki Y, Ohta T, Miura C (2006). "Progestin is an essential factor for the initiation of the meiosis in spermatogenetic cells of the eel". Proc. Natl. Acad. Sci. U.S.A. 103 (19): 7333–8. doi:10.1073/pnas.0508419103. PMC 1464341. PMID 16651536.
  6. 1 2 3 Raimondi SG, Olivier NS, Patrito LC, Flury A (1989). "Regulation of the 3 beta-hydroxysteroid dehydrogenase activity in tissue fragments and microsomes from human term placenta: kinetic analysis and inhibition by steroids". J. Steroid Biochem. 32 (3): 413–20. doi:10.1016/0022-4731(89)90215-X. PMID 2523011.
  7. 1 2 3 4 5 6 Sippell WG, Dörr HG, Bidlingmaier F, Knorr D (1980). "Plasma levels of aldosterone, corticosterone, 11-deoxycorticosterone, progesterone, 17-hydroxyprogesterone, cortisol, and cortisone during infancy and childhood". Pediatr. Res. 14 (1): 39–46. doi:10.1203/00006450-198014010-00010. PMID 7360520.
  8. 1 2 Bridges NA, Hindmarsh PC, Pringle PJ, Honour JW, Brook CG (1998). "Cortisol, androstenedione (A4), dehydroepiandrosterone sulphate (DHEAS) and 17 hydroxyprogesterone (17OHP) responses to low doses of (1-24)ACTH". J. Clin. Endocrinol. Metab. 83 (10): 3750–3. doi:10.1210/jc.83.10.3750. PMID 9768696.
  9. 1 2 Harding CF, Sheridan K, Walters MJ (1983). "Hormonal specificity and activation of sexual behavior in male zebra finches". Hormones and Behavior 17 (1): 111–33. doi:10.1016/0018-506X(83)90021-1. PMID 6862388.
  10. ↑ Desprez D.1, Geraz E., Hoareau M.C., Melard C., Bosc P., Baroiller J.F. (2003). "Production of a high percentage of male offspring with a natural androgen, 11beta-hydroxyandrostenedione (11betaOHA4), in Florida red tilapia". Aquaculture 216 (1): 55–65. doi:10.1016/S0044-8486(02)00276-4.
  11. ↑ Govoroun M, McMeel OM, D'Cotta H, et al. (2001). "Steroid enzyme gene expressions during natural and androgen-induced gonadal differentiation in the rainbow trout, Oncorhynchus mykiss". J. Exp. Zool. 290 (6): 558–66. doi:10.1002/jez.1106. PMID 11748604.
  12. 1 2 D. Consten, E.D. Keuning, M. Terlou, J.G.D. Lambert, H.J.Th. Goos (2001). "Cortisol effects on the testicular androgen synthesizing capacity in common carp, Cyprinus carpio L.". Fish Physiology and Biochemistry 25 (2): 91–98. doi:10.1023/A:1020538729104.
  13. ↑ Matthiesson KL, Stanton PG, O'Donnell L, et al. (2005). "Effects of testosterone and levonorgestrel combined with a 5alpha-reductase inhibitor or gonadotropin-releasing hormone antagonist on spermatogenesis and intratesticular steroid levels in normal men". J. Clin. Endocrinol. Metab. 90 (10): 5647–55. doi:10.1210/jc.2005-0639. PMID 16030154.
  14. ↑ Pringle AK, Schmidt W, Deans JK, Wulfert E, Reymann KG, Sundstrom LE (2003). "7-Hydroxylated epiandrosterone (7-OH-EPIA) reduces ischaemia-induced neuronal damage both in vivo and in vitro". Eur. J. Neurosci. 18 (1): 117–24. doi:10.1046/j.1460-9568.2003.02734.x. PMID 12859344.
  15. 1 2 Labrie C, Simard J, Zhao HF, Belanger A, Pelletier G, Labrie F (1989). "Stimulation of androgen-dependent gene expression by the adrenal precursors dehydroepiandrosterone and androstenedione in the rat ventral prostate". Endocrinology 124 (6): 2745–54. doi:10.1210/endo-124-6-2745. PMID 2524377.
  16. 1 2 Dumitrescu A, Aberdeen GW, Pepe GJ, Albrecht ED (2007). "Developmental expression of cell cycle regulators in the baboon fetal adrenal gland". J. Endocrinol. 192 (1): 237–47. doi:10.1677/joe.1.06769. PMID 17210761.
  17. ↑ Nuck BA, Lucky AW (1987). "Epitestosterone: a potential new antiandrogen". J. Invest. Dermatol. 89 (2): 209–11. doi:10.1111/1523-1747.ep12470564. PMID 3598212.
  18. 1 2 Perusquía M (2003). "Androgen-induced vasorelaxation: a potential vascular protective effect". Exp. Clin. Endocrinol. Diabetes 111 (2): 55–9. doi:10.1055/s-2003-39229. PMID 12746753.
  19. ↑ T.T. Wong, Y. Zohar (2003). "The involvement of gonadotropin receptors in sex reversal: expression, distribution and regulation of gonadal FSH and LH receptors in the gilthead seabream". Fish Physiology and Biochemistry 28: 179–180. doi:10.1023/B:FISH.0000030520.60240.cd.
  20. ↑ Lokman PM, Harris B, Kusakabe M, et al. (2002). "11-Oxygenated androgens in female teleosts: prevalence, abundance, and life history implications". Gen. Comp. Endocrinol. 129 (1): 1–12. doi:10.1016/S0016-6480(02)00562-2. PMID 12409090.
  21. ↑ Thomas RM, Urban JH, Peterson DA (2006). "Acute exposure to predator odor elicits a robust increase in corticosterone and a decrease in activity without altering proliferation in the adult rat hippocampus". Exp. Neurol. 201 (2): 308–15. doi:10.1016/j.expneurol.2006.04.010. PMID 16750196.
  22. ↑ Reardon GE, Caldarella AM, Canalis E (1979). "Determination of serum cortisol and 11-deoxycortisol by liquid chromatography" (PDF). Clin. Chem. 25 (1): 122–6. PMID 761348.
  23. ↑ Auchus RJ, Chandler DW, Singeetham S, et al. (2007). "Measurement of 18-Hydroxycorticosterone During Adrenal Vein Sampling for Primary Aldosteronism". Journal of Clinical Endocrinology & Metabolism 92 (7): 2648–51. doi:10.1210/jc.2006-2631. PMID 17473070.
  24. ↑ Krishnan AV, Zhao XY, Swami S, et al. (2002). "A glucocorticoid-responsive mutant androgen receptor exhibits unique ligand specificity: therapeutic implications for androgen-independent prostate cancer". Endocrinology 143 (5): 1889–1900. doi:10.1210/en.143.5.1889. PMID 11956172.
  25. ↑ Nunez S, Trant JM (1999). "Regulation of interrenal gland steroidogenesis in the Atlantic stingray (Dasyatis sabina)". J. Exp. Zool. 284 (5): 517–25. doi:10.1002/(SICI)1097-010X(19991001)284:5<517::AID-JEZ7>3.0.CO;2-S. PMID 10469989.
  26. ↑ Kornel L, Smoszna-Konaszewska B (1995). "Aldosterone (ALDO) increases transmembrane influx of Na+ in vascular smooth muscle (VSM) cells through increased synthesis of Na+ channels". Steroids 60 (1): 114–9. doi:10.1016/0039-128X(94)00016-6. PMID 7792795.

Further reading

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