Listeria Hfq binding LhrC

Listeria Hfq binding LhrC
Predicted secondary structure and sequence conservation of LhrC
Identifiers
Symbol LhrC
Rfam RF00616
Other data
RNA type Gene; sRNA
Domain(s) Bacteria
SO 0000655

Listeria Hfq binding LhrC this ncRNA was identified by screening for RNA molecules which co-immunoprecipitated with the RNA chaperone Hfq.[1] This RNA is transcribed from an intergenic region between the protein coding genes cysK, a putative cysteine synthase and sul, a putative dihydropteroate synthase. In Listeria monocytogenes four additional copies of lhrC have been identified in the genome, three of which are located in tandem repeat upstream of the originally characterised lhrC. This RNA molecule appears to be conserved amongst Listeria species but has not been identified in other bacterial species. It is involved in virulence.[2]

See also

References

  1. ↑ Christiansen JK, Nielsen JS, Ebersbach T, Valentin-Hansen P, Søgaard-Andersen L, Kallipolitis BH (2006). "Identification of small Hfq-binding RNAs in Listeria monocytogenes". RNA 12 (7): 1383–96. doi:10.1261/rna.49706. PMC 1484441. PMID 16682563.
  2. ↑ Sievers, S; Lillebæk, EM; Jacobsen, K; Lund, A; Mollerup, MS; Nielsen, PK; Kallipolitis, BH (Jul 17, 2014). "A multicopy sRNA of Listeria monocytogenes regulates expression of the virulence adhesin LapB.". Nucleic Acids Research 42: 9383–98. doi:10.1093/nar/gku630. PMID 25034691.

External links


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