| | From | Until | Remarks |
| Alexander Mylne, Abbot of Cambuskenneth | 1532 | 1543 | Abbot of Cambuskenneth (1519–1548) |
| Robert Reid, Bishop of Orkney | 1543 | 1558 | Abbot of Kinloss (1528–1553); Commendator of Beauly (1531–1553); Bishop of Orkney (1541–1558) |
| Henry Sinclair, Bishop of Ross | 1558 | 1565 | Commendator of Kilwinning (1541–1550); Dean of Glasgow (1550–1561); Bishop of Ross (1558–1565) |
| John Sinclair, Bishop of Brechin | 1565 | 1566 | Appointed a Lord of Session, 1540; Bishop of Brechin (1565–1566) |
| William Baillie, Lord Provand | 1566 | 1567 | |
| James Balfour, Lord Pittendreich | 1567 | 1593 | Appointed a Lord of Session, 1561 |
| Alexander Seton, Lord Fyvie | 1593 | 1604 | Appointed a Lord of Session, 1586; Provost of Edinburgh (1598–1608); Lord Chancellor of Scotland (1604–1622); Lord High Commissioner to the Parliament of Scotland (1612–1621) |
| James Elphinstone, 1st Lord Balmerino | 1605 | 1609 | Appointed a Lord of Session, 1587; Secretary of State (1598–1609) |
| John Preston, Lord Fentonbarns | 1609 | 1616 | Appointed a Lord of Session, 1595 |
| Thomas Hamilton, 1st Earl of Melrose | 1616 | 1625 | Appointed a Lord of Session, 1592; Lord Advocate (1595–1596 and 1596–1612); Lord Clerk Register (1612) |
| Sir James Skene of Curriehill | 1626 | 1633 | Lord Clerk Register (1594–1612); Appointed a Lord of Session, 1594 |
| Robert Spottiswood, Lord Newabbey | 1633 | 1646 | Appointed a Lord of Session, 1622 |
| Sir John Gilmour of Craigmillar | 1661 | 1671 | Commissioner for Edinburghshire (1661–1671) |
| James Dalrymple, 1st Viscount Stair | 1671 | 1681 | Appointed a Lord of Session, 1661; Commissioner for Wigtownshire (1672–1674, 1678 and 1681–1682) |
| George Gordon, 1st Earl of Aberdeen | 1681 | 1682 | Commissioner for Aberdeenshire (1669–1674, 1678 and 1681–1682); Appointed a Lord of Session, 1680; Lord Chancellor of Scotland (1682–1684) |
| Sir David Falconer of Newton | 1682 | 1685 | Appointed a Lord of Session, 1676; Commissioner for Forfarshire (1685) |
| Sir George Lockhart of Carnwath | 1685 | 31 March 1689 | Appointed Dean of the Faculty of Advocates, 1672; Commissioner for Lanarkshire (1681–1682 and 1685–1686) |
| James Dalrymple, 1st Viscount Stair | 28 October 1689 | 25 November 1695 | Appointed a Lord of Session, 1661; Commissioner for Wigtownshire (1672–1674, 1678 and 1681–1682) |
| Hew Dalrymple, Lord North Berwick | 17 March 1698 | 20 June 1737 | Commissioner for New Galloway (1690–1702); Dean of the Faculty of Advocates (1695–1698); Commissioner for North Berwick (1702–1707) |
| Duncan Forbes, Lord Culloden | 20 June 1737 | 4 June 1748 | MP for Ayr Burghs (1721–1722); MP for Inverness Burghs (1722–1737); Lord Advocate (1725–1737) |
| Robert Dundas, Lord Arniston the Elder | 4 June 1748 | 26 August 1753 | Solicitor General for Scotland (1717–1720); Lord Advocate (1720–1725); MP for Midlothian (1722–1737); Senator of the College of Justice (1737–1753) |
| Robert Craigie, Lord Glendoick | 22 January 1754 | 10 March 1760 |
MP for Tain Burghs (1742–1747); Lord Advocate (1742–1746) |
| Robert Dundas, Lord Arniston the Younger | 30 April 1760 | 13 December 1787 | Solicitor General for Scotland (1742–1746); Dean of the Faculty of Advocates (1746–1760) Lord Advocate (1754–1760); MP for Midlothian (1754–1760) |
| Thomas Miller, Lord Glenlee | 22 December 1787 | 27 September 1789 | MP for Dumfries Burghs (1761–1766); Solicitor General for Scotland (1759–1760); Lord Advocate (1760–1766); Lord Justice Clerk (1766–1787) |
| Ilay Campbell, Lord Succoth | 26 October 1789 | 31 August 1808 | Solicitor General for Scotland (1783–1784); MP for Clyde Burghs (1784–1790); Lord Advocate (1784–1789) |
| Robert Blair, Lord Avontoun | 31 August 1808 | 20 May 1811 | Solicitor General for Scotland (1789–1806); Dean of the Faculty of Advocates (1801–1808) |
| Charles Hope, Lord Granton | 10 October 1811 | 20 July 1841 | Lord Advocate (1801–1804); MP for Dumfries Burghs (1802); MP for Edinburgh (1803–1805); Lord Justice Clerk (1804–1811) |
| David Boyle, Lord Boyle | 7 October 1841 | 5 May 1852 | MP for Ayrshire (1807–1811); Solicitor General for Scotland (1807–1811); Lord Justice Clerk (1811–1841) |
| Duncan McNeill, Lord Colonsay | 14 May 1852 | 25 February 1867 | MP for Argyllshire (1843–1851); Solicitor General for Scotland (1834–1835 & 1841–1842); Lord Advocate (1842–1846) |
| John Inglis, Lord Glencorse | 25 February 1867 | 20 August 1891 | MP for Stamford (1858); Solicitor General for Scotland (1852); Lord Advocate (1852 & 1858); Lord Justice Clerk (1858–1867) |
| James Robertson, Lord Robertson | 21 September 1891 | 21 November 1899 | MP for Buteshire (1885–1891); Solicitor General for Scotland (1885–1886 & 1886–1888); Lord Advocate (1888–1891); Lord of Appeal in Ordinary (1899–1909) |
| John Balfour, 1st Baron Kinross | 21 November 1899 | 22 January 1905 | MP for Clackmannan and Kinross (1880–1899); Solicitor General for Scotland (1880–1881); Lord Advocate (1881–1885, 1886 & 1892–1895) |
| Andrew Murray, 1st Baron Dunedin | 4 February 1905 | 14 October 1913 | MP for Buteshire (1891–1905); Solicitor General for Scotland (1905–1909); Lord Advocate (1909–1913); Secretary for Scotland (1903–1905); Lord of Appeal in Ordinary (1913–1932) |
| Alexander Ure, 1st Baron Strathclyde | 14 October 1913 | 1 April 1920 | MP for Linlithgowshire (1895–1913); Solicitor General for Scotland (1891–1892 & 1895–1896); Lord Advocate (1896–1903) |
| James Avon Clyde, Lord Clyde | 1 April 1920 | 1 April 1935 | Solicitor General for Scotland (1905); MP for Edinburgh West (1909–1918) and Edinburgh North (1918–1920); Lord Advocate (1916–1920) |
| Wilfred Normand, Lord Normand | 1 April 1935 | 6 January 1947 | MP for Edinburgh West (1931–1935); Solicitor General for Scotland (1929 & 1931–1933); Lord Advocate (1933–1935); Lord of Appeal in Ordinary (1947–1953) |
| Thomas Cooper, Lord Cooper[7] | 6 January 1947 | 23 December 1954 | MP for Edinburgh West (1935–1941); Solicitor General for Scotland (1935); Lord Advocate (1935–1941); Senator of the College of Justice (1941–1954); Lord Justice Clerk (1947–1954) |
| James Latham Clyde, Lord Clyde[8] | 23 December 1954 | 25 April 1972 | MP for Edinburgh North (1950–1954); Lord Advocate (1951–1954); Senator of the College of Justice (1954–1972) |
| George Emslie, Baron Emslie[9] | 25 April 1972 | 27 September 1989 | Dean of the Faculty of Advocates (1965–1970); Senator of the College of Justice (1970–1989) |
| David Hope, Baron Hope of Craighead | 27 September 1989 | 1 October 1996 | Dean of the Faculty of Advocates (1986–1989); Senator of the College of Justice (1989–1996); Lord of Appeal in Ordinary (1996–2009); Second Senior Law Lord (2009); Deputy President of the Supreme Court (2009–2013) |
| Alan Rodger, Baron Rodger of Earlsferry | 1 October 1996 | 13 November 2001 | Solicitor General for Scotland (1989–1992); Lord Advocate (1992–1995); Senator of the College of Justice (1995–2001); Lord of Appeal in Ordinary (2001–2009); Justice of the Supreme Court (2009–2011) |
| William Cullen, Baron Cullen of Whitekirk | 13 November 2001 | 2 December 2005 | Chairman of the Medical Appeals Tribunals (1977–1986); Senator of the College of Justice (1986–2005); Lord Justice Clerk (1997–2001) |
| Arthur Hamilton, Lord Hamilton | 2 December 2005 | 8 June 2012 | Chairman of the Medical Appeals Tribunals (1988–1992); President of the Pensions Appeal Tribunal in Scotland (1992–1995); Senator of the College of Justice (1995–2012) |
| Brian Gill, Lord Gill | 8 June 2012 | 31 May 2015 | Senator of the College of Justice (1994–2015); Lord Justice Clerk (2001–2012) |
| Colin Sutherland, Lord Carloway | 18 December 2015 | present | Senator of the College of Justice (2000–present); Lord Justice Clerk (2012–2015) |