Louping ill
| Louping ill virus | |
|---|---|
| Virus classification | |
| Group: | Group IV ((+)ssRNA) |
| Family: | Flaviviridae |
| Genus: | Flavivirus |
| Species: | Louping ill virus |
| Louping ill | |
|---|---|
| Classification and external resources | |
| Specialty | Infectious disease |
| ICD-10 | A84.8 |
| ICD-9-CM | 063.1 |
| DiseasesDB | 7591 |
| MeSH | D008146 |
Louping-ill (also known as Ovine Encephalomyelitis, Infectious Encephalomyelitis of Sheep, Trembling-ill) is an acute viral disease primarily of sheep that is characterized by a biphasic fever, depression, ataxia, muscular incoordination, tremors, posterior paralysis, coma, and death. Louping-ill is a tick-transmitted disease whose occurrence is closely related to the distribution of the primary vector, the sheep tick Ixodes ricinus. It also causes disease in red grouse, and can affect humans. The name 'louping-ill' is derived from an old Scottish word describing the effect of the disease in sheep whereby they 'loup' or spring into the air.[1]
Etiology
Louping ill is caused by RNA virus called Louping ill virus. Louping ill virus belongs to genus Flavivirus,[2] family Flaviviridae.
There are four subtypes: British, Irish, Spanish and Turkish.
Prevention
According to a ProMED article,[3] disease in sheep has been controlled in the UK by a vaccine (ATCvet code: QI04AA01), originally developed by Scotland's Moredun Research Institute. In 2009, however, a shortage of vaccine combined with an increase in the number of ticks found in sheep pasture areas cause an increased risk of this disease.
References
- ↑ Health Protection Agency. Louping ill. Background information. Last reviewed: 8 August 2008. Last viewed 23 April 2009. Archived May 31, 2009, at the Wayback Machine.
- ↑ Charrel RN, Attoui H, Butenko AM; et al. (December 2004), "Tick-borne virus diseases of human interest in Europe", Clin. Microbiol. Infect. 10 (12): 1040–55, doi:10.1111/j.1469-0691.2004.01022.x, PMID 15606630.
- ↑ ProMED Archive Number 20090420.1492, Published Date 20-APR-2009, Subject PRO/AH> Louping ill - UK: vaccination
- Committee on Foreign Animal Diseases of the United States Animal Health Association (1998), Foreign Animal Diseases, Pat Campbell & Assoc/Carter Printing Co, ISBN 0-08-615213-0, archived from the original on 2009-02-14
- Louping ill (pdf), Center for Food Security and Public Health, College of Veterinary Medicine, Iowa State University, 2005-08-05
External links
- Moredun Research Institute vaccine article
- WHO vaccine listing: QI04AA01 (WHO))