Lymphoblastic lymphoma

Lymphoblastic lymphoma
Classification and external resources
eMedicine	article/203556
MeSH	D054198

Lymphoblastic lymphoma is a rare type of non-Hodgkin lymphoma, a result of abnormal adaptive immune cells, typically T-cells. It usually occurs in children.

Hematological malignancy/leukemia histology (ICD-O 9590–9989, C81–C96, 200–208)
Lymphoid/Lymphoproliferative, Lymphomas/Lymphoid leukemias (9590–9739, 9800–9839)

B cell
(lymphoma,
leukemia)
(most CD19

CD20)

By
development/
marker

TdT+	ALL (Precursor B acute lymphoblastic leukemia/lymphoma)

CD5+	naive B cell (CLL/SLL) mantle zone (Mantle cell)

CD22+	Prolymphocytic CD11c+ (Hairy cell leukemia)

CD79a+	germinal center/follicular B cell (Follicular Burkitt's GCB DLBCL Primary cutaneous follicle center lymphoma) marginal zone/marginal zone B-cell (Splenic marginal zone MALT Nodal marginal zone Primary cutaneous marginal zone lymphoma)

RS (CD15+, CD30+)	Classic Hodgkin's lymphoma (Nodular sclerosis) CD20+ (Nodular lymphocyte predominant Hodgkin's lymphoma)

PCDs/PP (CD38+/CD138+)	see immunoproliferative immunoglobulin disorders

By infection

KSHV (Primary effusion)
EBV (Lymphomatoid granulomatosis
Post-transplant lymphoproliferative disorder)
HIV (AIDS-related lymphoma)
Helicobacter pylori (MALT lymphoma)

Cutaneous

T/NK

T cell
(lymphoma,
leukemia)
(most CD3

CD4
CD8)

By
development/
marker

TdT+: ALL (Precursor T acute lymphoblastic leukemia/lymphoma)

prolymphocyte (Prolymphocytic)

Cutaneous

MF+variants	indolent: Mycosis fungoides Pagetoid reticulosis Granulomatous slack skin aggressive: Sézary disease Adult T-cell leukemia/lymphoma

Non-MF	CD30-: Non-mycosis fungoides CD30− cutaneous large T-cell lymphoma Pleomorphic T-cell lymphoma Lymphomatoid papulosis type B CD30+: CD30+ cutaneous T-cell lymphoma Secondary cutaneous CD30+ large-cell lymphoma Lymphomatoid papulosis type A

Other
peripheral

By infection

HTLV-1 (Adult T-cell leukemia/lymphoma)

NK cell/
(most CD56)

T or NK

Lymphoid+
myeloid

Acute biphenotypic leukaemia

Lymphocytosis

Cutaneous lymphoid hyperplasia

Treatment is usually chemotherapy preferably HYPER CVAD regimen

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