Metrizoic acid

Metrizoic acid
Systematic (IUPAC) name


3-(acetylamino)-5-[acetyl(methyl)amino]-2,4,6-triiodobenzoic acid
Identifiers
CAS Number	1949-45-7
ATC code	V08AA02 (WHO)
PubChem	CID 2528
ChemSpider	2433
KEGG	C14165
ChEBI	CHEBI:34847
ChEMBL	CHEMBL1736^Y
Chemical data
Formula	C₁₂H₁₁I₃N₂O₄
Molar mass	627.94 g/mol
SMILES CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)N(C)C(=O)C)I
InChI InChI=1S/C12H11I3N2O4/c1-4(18)16-10-7(13)6(12(20)21)8(14)11(9(10)15)17(3)5(2)19/h1-3H3,(H,16,18)(H,20,21) Key:GGGDNPWHMNJRFN-UHFFFAOYSA-N

Metrizoic acid is a molecule used as a contrast medium. Due to its high osmolality, Metrizoic acid has a risk of inducing allergic reactions compared to lower osmolar contrast media.

Contrast media (V08)

X-ray and CT

Iodinated,
Water soluble

Nephrotropic, high osmolar	Diatrizoic acid^# Metrizoic acid Iodamide Iotalamic acid Ioxitalamic acid Ioglicic acid Acetrizoic acid Iocarmic acid Methiodal Diodone

Nephrotropic, low osmolar	Metrizamide Iohexol^# Ioxaglic acid Iopamidol Iopromide Iotrolan Ioversol Iopentol Iodixanol Iomeprol Iobitridol Ioxilan

Hepatotropic	Iodoxamic acid Iotroxic acid Ioglycamic acid Adipiodone Iobenzamic acid Iopanoic acid Iocetamic acid Sodium iopodate Tyropanoic acid Calcium iopodate

Iodinated,
Water insoluble

Non-iodinated

Barium sulfate^#

MRI

Paramagnetic	Gadolinium-based: Gadobenic acid Gadobutrol Gadodiamide Gadofosveset Gadolinium Gadopentetic acid Gadoteric acid Gadoteridol Gadoversetamide Gadoxetic acid Other: Ferric ammonium citrate Mangafodipir

Superparamagnetic	Ferumoxsil Ferristene Iron oxide, nanoparticles

Other	Perflubron

Ultrasound

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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