Monocytopenia

Monocytopenia
Classification and external resources
ICD-9-CM	288.59
DiseasesDB	29083

Monocytopenia is a form of leukopenia associated with a deficiency of monocytes. The causes of monocytopenia include: acute infections, stress, treatment with glucocorticoids, aplastic anemia, hairy cell leukemia, acute myeloid leukemia, treatment with myelotoxic drugs and genetic syndromes, as for example MonoMAC syndrome.^[1]

It has been proposed as a measure to predict neutropenia,^[2] though some research indicates that it is less effective than lymphopenia.^[3]

References

1. Harrison's principles of internal medicine. New York: McGraw-Hill. 2005. p. 356. ISBN 0-07-140235-7.
2. Kondo M, Oshita F, Kato Y, Yamada K, Nomura I, Noda K (1999). "Early monocytopenia after chemotherapy as a risk factor for neutropenia". Am. J. Clin. Oncol. 22 (1): 103–5. doi:10.1097/00000421-199902000-00025. PMID 10025393.
3. Oguz A, Karadeniz C, Ckitak EC, Cil V (2006). "Which one is a risk factor for chemotherapy-induced febrile neutropenia in childhood solid tumors: early lymphopenia or monocytopenia?". Pediatr Hematol Oncol 23 (2): 143–51. doi:10.1080/08880010500457673. PMID 16651243.