Movat's stain
Movat's stain is a pentachrome stain originally developed by Henry Zoltan Movat[1] in 1955 to highlight the various constituents of connective tissue, especially cardiovascular tissue, by five colors in a single stained slide.[2] In 1972, H. K. Russell, Jr. modified the technique so as to reduce the time for staining and to increase the consistency and reliability of the staining.[3]
| Colour | Tissue type |
|---|---|
| Black | Nuclei; elastic fibres |
| Yellow | Collagen fibres; reticular fibres |
| Blue | Ground substance; mucin |
| Bright red | Fibrin |
| Red | Muscle |
Gallery
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Movat's stain showing amyloid (brown) and fibrosis (yellow) of the heart.
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Movat's stain showing thickening of the spongiosa layer (blue) in myxomatous degeneration of the aortic valve.
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Movat's stain showing luminal stenosis in coronary artery atherosclerosis.
References
- ↑ "Pathology News: Newsletter, Vol. 3, No. 4: April 1996" (PDF). Department of Pathology and Molecular Medicine, Queen's University.
- ↑ Movat, HZ (1955). "Demonstration of all connective tissue elements in a single section; pentachrome stains". AMA Archives of Pathology 60 (3): 289–95. PMID 13248341.
- ↑ Russell Jr, HK (1972). "A modification of Movat's pentachrome stain". Archives of Pathology 94 (2): 187–91. PMID 4114784.
- ↑ "Penn MCRC > Modified Movat's Pentachrome Stain". Perelman School of Medicine, the University of Pennsylvania. Retrieved 2012-08-08.
See also
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