Oxazolidinedione

2,4-Oxazolidenedione
Names


IUPAC name 1,3-Oxazolidine-2,4-dione
Other names 2,4-Oxazolidenedione
Identifiers
CAS Number	2346-26-1^Y
ChemSpider	87905^Y
Jmol interactive 3D	Image
PubChem	97389
InChI InChI=1S/C3H3NO3/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6)^Y Key: COWNFYYYZFRNOY-UHFFFAOYSA-N^Y InChI=1S/C3H3NO3/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6) Key: COWNFYYYZFRNOY-UHFFFAOYSA-N
SMILES O=C1NC(=O)OC1
Properties
Chemical formula	C₃H₃NO₃
Molar mass	101.06 g·mol⁻¹
Boiling point	89 to 90 °C (192 to 194 °F; 362 to 363 K)^[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is ^YN ?)
Infobox references

Oxazolidinedione is a heterocyclic chemical compound that forms the core structure of a variety anticonvulsant drugs including:

Ethadione
Paramethadione
Trimethadione

References

↑ Traube, Wilhelm (1913). "Über das Isohydantoin 2-Imino-4-keto-tetrahydro-oxazol und seine Homologen". Berichte der Deutschen Chemischen Gesellschaft 46: 2077–2084. doi:10.1002/cber.191304602124.

Anticonvulsants (N03)

GABAergics

GABA_AR PAMs	Barbiturates: Barbexaclone Metharbital Methylphenobarbital Pentobarbital Phenobarbital^# Primidone; Carbamates: Felbamate; Benzodiazepines: Clobazam Clonazepam Clorazepate Diazepam^# Lorazepam^# Midazolam Nimetazepam Nitrazepam Temazepam; Others: Bromide (potassium bromide, sodium bromide) Paraldehyde Stiripentol

GABA-T inhibitors	Fatty acids: Valproate Valpromide Valproate pivoxil; Others: Ethanolamine-O-sulfate Vigabatrin

Others	GABAR agonists: Progabide; GAT-1 inhibitors: Tiagabine

Channelergics

Sodium blockers	Hydantoins: Ethotoin Fosphenytoin Mephenytoin Phenytoin^#; Ureides: Acetylpheneturide Chlorphenacemide Phenacemide^‡ Pheneturide; Fatty acids: Valproate Valpromide Valproate pivoxil; Carboxamides: Carbamazepine^# Eslicarbazepine acetate Oxcarbazepine; Others: Lacosamide Lamotrigine Rufinamide Topiramate Zonisamide

Calcium blockers	Oxazolidinediones: Ethadione Paramethadione Trimethadione; Succinimides: Ethosuximide^# Mesuximide Phensuximide; Gabapentinoids: Gabapentin Pregabalin; Others: Lamotrigine Topiramate Zonisamide

Potassium openers	Retigabine

Others

CA inhibitors	Sulfonamides: Acetazolamide Ethoxzolamide Sultiame Topiramate Zonisamide

Others	Beclamide Brivaracetam Levetiracetam Perampanel

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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