Porokeratosis

Porokeratosis

A porokeratosis lesion in a patient with disseminated superficial actinic porokeratosis.
Classification and external resources
OMIM 175800, 175850 175860, 175800, 175850
DiseasesDB 33408, 32454, 34839.htm 31356, 33408, 32454, 34839
eMedicine article/1059123
MeSH D017499

Porokeratosis (or parakeratosis) is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer.[1]:532

Types

Porokeratosis may be divided into the following clinical types:[1]:532

Pathology

Micrograph of a case of porokeratosis showing a characteristic cornoid lamella (dark pink/red structure in the right/upper portion of the image). H&E stain.

Porokeratosis has a characteristic histomorphologic feature known as a cornoid lamella.

See also

References

  1. 1 2 3 4 5 6 7 8 Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
  2. 1 2 3 4 Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 1668. ISBN 1-4160-2999-0.
  3. 1 2 3 4 James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  4. 1 2 Familial disseminated plaque type porokeratosis with multiple horns and squamous cell carcinoma involving anal skin
  5. Lemont H (2008). "What's your diagnosis? Porokeratosis plantaris discreta (Steinberg's lesion)". J Am Podiatr Med Assoc 98 (4): 337–8. PMID 18685058.
  6. Taub J, Steinberg MD (1970). "Porokeratosis plantaris discreta, a previously unrecognized dermatopathological entity". Int. J. Dermatol. 9 (2): 83–90. doi:10.1111/j.1365-4362.1970.tb04584.x. PMID 5426632.

External links

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