Pneumovirus
| Pneumovirus | |
|---|---|
| Virus classification | |
| Group: | Group V ((-)ssRNA) |
| Order: | Mononegavirales |
| Family: | Paramyxoviridae |
| Subfamily: | Pneumovirinae |
| Genus: | Pneumovirus |
The genus Pneumovirus consists of pathogens that work to target the upper respiratory tract within their specific host species. Every pneumovirus is characterized as host specific, and has a range of diseases involved with respiratory illness. Pneumoviruses can range from a less-severe upper-respiratory illness to severe bronchiolitis or pneumonia. Pneumoviruses are found among sheep, cows, and most importantly humans. In humans, the pneumovirus that specifically impacts infants and small children known as the Human respiratory syncytial virus.[1] Pneumoviruses have been traced by researchers from the Center for Disease Control and the University Medica Centre in Utrecht, Netherlands on how pneumoviruses attack infants and small children.[2][3]
Characteristics
The Pneumovirus genus is part of the Paramyxoviridae family of viruses which contain 3 segments of -ssRNA. Pneumoviruses are found specifically in the species of Homo sapiens, Ovis aries Capra aegagrus hircus, Bos primigenius, and Rodentia.
The most common pneumoviruses are as follows:
•Homo sapiens = Human respiratory syncytial virus
•Bos primigenius = Bovine respiratory syncytial virus
•Ovis aries = Ovine respiratory syncytial virus
•Capra aegagrus hircus = Caprine respiratory syncytial virus
•Rodentia = Pneumonia virus of mice
Symptoms
Mild symptoms may include rhinitis, coughing, and decreased appetite. More serious symptoms include wheezing, difficulty breathing, fever, bronchiolitis and pneumonia.[4]
Risk Factors
Having a weak immune system and pre-existing conditions such as asthma can be leading factors in catching a pneumovirus. In elderly adults, having chronic heart or lung disease is also risk factor. Being in close proximity to a host who has been infected with a pneumovirus can also be a risk since most transmission happens via respiratory.
Diagnosis
Transmission of an infectious agent by another person or animal can be through blood, needles, blood transfusion, a mother to fetus, coughing, sneezing, saliva, or air transmission. Healthcare providers will determine the severity of the virus and possible treatment options. Healthcare providers will also decide if hospitalization is needed for more intense cases.[2][4][5][6]
Treatment
Treatment plans are not specific and are based upon a specific host's current symptoms. Antibiotics and isolation are the first course of action for the infected host. In more serious cases, supplemental oxygen may be used to aid in oxygen intake. In severe viral detection, intubation and the use of a mechanical ventilation will be inserted as a breathing apparatus.[2]
Prevention
The best methods of prevention for pneumoviruses are covering cough and sneezing to prevent transmission of possible pathogens. Isolating animals and humans that have a pneumovirus is the best way to prevent the virus from spreading. Molecular studies have been on the rise due to continuing materials and information obtained regarding recombinant DNA arrangements that might offer a foundation for vaccine development. Currently animals are able to receive vaccines specific to their virus strand. During cold and peak flu season, infants and small children have the option to receive monthly injections of small medication doses at a weak strength to help prevent virus/ host attachment.[7][8]
Cases
Human respiratory syncytial virus (RSV) is the most known Pneumovirus because of its direct correlation and importance in humans. RSV is the leading viral agent among pneumoviruses in pediatric upper respiratory diseases globally. New pneumoviruses have been discovered in the Netherlands among 28 children according to studies. Certain studies have isolated the children in hospitals to identify specific causes, contagion levels, and treatment options among those children.[1]
References
- 1 2 Van Den Hoogen, Bernadette G.; De Jong, Jan C.; Groen, Jan; Kuiken, Thijs; De Groot, Ronald; Fouchier, Ron A.M.; Osterhaus, Albert D.M.E. (2001). "A newly discovered human pneumovirus isolated from young children with respiratory tract disease". Nature Medicine 7 (6): 719–24. doi:10.1038/89098. PMID 11385510.
- 1 2 3 http://www.cdc.gov/rsv/about.infection.html[]
- ↑ A.C. van de Pol, Wilhelmina Children's Hpspital, Dept. of Paediatrics, University Medica Centre Utrecht, Netherlands
- 1 2 Bennett, Nicholas; Ellis, John; Bonville, Cynthia; Rosenberg, Helene; Domachowske, Joseph (2007). "Immunization strategies for the prevention of pneumovirus infections". Expert Review of Vaccines 6 (2): 169–82. doi:10.1586/14760584.6.2.169. PMID 17408367.
- ↑ http://www.healthline.com/health/disease-transmission#Overview1[]
- ↑ McIntosh, K. M.; Chanock, R. M. (1985). "Respiratory Synoytial Virus". In Fields, Bernard N.; Knipe, David M.; Chanock, Robert M.; Hirsch, Martin S.; Melnick, Joseph L.; Monath, Thomas P.; Roizman, Bernard; Howley, Peter M.; Griffin, Diane E. Fields Virology. New York: Raven Press. pp. 1285–304. ISBN 978-0-88167-552-8.
- ↑ medical-dectionary.thefreedictionary.com/pneuvovirus
- ↑ Collins, Peter L. (1991). "The Molecular Biology of Human Respiratory Syncytial Virus (RSV) of the Genus Pneumovirus". In Kingsbury, David W. The Paramyxoviruses. The Viruses. pp. 103–62. doi:10.1007/978-1-4615-3790-8_4. ISBN 978-1-4613-6689-8.