Promoxolane

Promoxolane
Systematic (IUPAC) name

2,2-diisopropyl-4-hydroxymethyl-1,3-dioxolane
Clinical data
Routes of administration	oral
Identifiers
CAS Number	470-43-9^Y
ATC code	none
PubChem	CID 10105
ChemSpider	9701
UNII	JHI9RRY52E^Y
Chemical data
Formula	C₁₀H₂₀O₃
Molar mass	188.264 g/mol
SMILES CC(C)C1(OCC(O1)CO)C(C)C
InChI InChI=1S/C10H20O3/c1-7(2)10(8(3)4)12-6-9(5-11)13-10/h7-9,11H,5-6H2,1-4H3 Key:HHFOOWPWAXNJNY-UHFFFAOYSA-N
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Promoxolane (Dimethylane) is a centrally acting muscle relaxant and anxiolytic drug.^[1]^[2]^[3]

References

↑ "Drug use in outpatient treatment." American Journal of Psychiatry, 124: 8, Feb. 1968
↑ "Dimethylane in the treatment of anxiety reactions." Dis Nerv Syst, 1957 Nov;18(11):434-9
↑ "2,2-Disubstituted 1,3-Dioxolanes and 2,2-Disubstituted 1,3-Dioxanes." R Meltzer et al, J. Org. Chem, 1960, 25 (5), 712-715

Skeletal muscle relaxants (M03)

Peripherally acting
(primarily antinicotinic,
NMJ block)

Non-depolarizing

Curare alkaloids	Alcuronium Dimethyltubocurarine Tubocurarine

4° ammonium agents	ultra-short duration: Gantacurium short duration: Mivacurium Chandonium intermediate duration: Atracurium Cisatracurium Fazadinium Rocuronium Vecuronium long duration: Doxacurium Dimethyltubocurarine Pancuronium Pipecuronium Laudexium Gallamine unsorted: Hexafluronium (Hexafluorenium)

Depolarizing

Choline derivatives: Suxamethonium (Succinylcholine)

Polyalkylene derivatives: Hexamethonium

ACh release inhibitors

Botulinum toxin

Centrally acting

Carbamic acid esters	Carisoprodol Cyclarbamate Difebarbamate Febarbamate Meprobamate Phenprobamate Styramate Tybamate

Benzodiazepines	Bromazepam Diazepam Clonazepam Flunitrazepam Lorazepam Nitrazepam Temazepam Tetrazepam

Nonbenzodiazepines	Eszopiclone

Thienodiazepines	Etizolam

Quinazolines	Methaqualone

Anticholinergics (Antimuscarinics)	Cyclobenzaprine Orphenadrine

Other	Arbaclofen placarbil Baclofen Chlormezanone Chlorphenesin Chlorzoxazone Donepezil Eperisone Fenyramidol Flopropione Gabapentin GHB Mephenesin Mephenoxalone Metaxalone Methocarbamol Phenibut Pregabalin Pridinol Promoxolane Quinine Thiocolchicoside Tizanidine Tolperisone

Directly acting

Dantrolene

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