Propanediol-phosphate dehydrogenase
| propanediol-phosphate dehydrogenase | |||||||||
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| Identifiers | |||||||||
| EC number | 1.1.1.7 | ||||||||
| CAS number | 9028-15-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a propanediol-phosphate dehydrogenase (EC 1.1.1.7) is an enzyme that catalyzes the chemical reaction
- propane-1,2-diol 1-phosphate + NAD+
hydroxyacetone phosphate + NADH + H+
Thus, the two substrates of this enzyme are propane-1,2-diol 1-phosphate and NAD+, whereas its 3 products are hydroxyacetone phosphate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is propane-1,2-diol-1-phosphate:NAD+ oxidoreductase. Other names in common use include PDP dehydrogenase, 1,2-propanediol-1-phosphate:NAD+ oxidoreductase, and propanediol phosphate dehydrogenase.
References
- Sellinger OZ and Miller ON (1959). "The metabolism of acetol phosphate. II. 1,2-Propanediol-1-phosphate dehydrogenase". J. Biol. Chem. 234 (7): 1641–1646. PMID 13672935.
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