Rentiapril

Rentiapril
Names


IUPAC name (2R,4R)-2-(2-hydroxyphenyl)-3-(3-sulfanylpropanoyl)-1,3-thiazolidine-4-carboxylic acid
Identifiers
CAS Number	72679-47-1^Y
ChemSpider	64376^N
Jmol interactive 3D	Image
PubChem	71244
UNII	D0TAM1017B^Y
InChI InChI=1S/C13H15NO4S2/c15-10-4-2-1-3-8(10)12-14(11(16)5-6-19)9(7-20-12)13(17)18/h1-4,9,12,15,19H,5-7H2,(H,17,18)/t9-,12+/m0/s1^N Key: BSHDUMDXSRLRBI-JOYOIKCWSA-N^N InChI=1/C13H15NO4S2/c15-10-4-2-1-3-8(10)12-14(11(16)5-6-19)9(7-20-12)13(17)18/h1-4,9,12,15,19H,5-7H2,(H,17,18)/t9-,12+/m0/s1 Key: BSHDUMDXSRLRBI-JOYOIKCWBM
SMILES C1[C@H](N([C@H](S1)C2=CC=CC=C2O)C(=O)CCS)C(=O)O
Properties
Chemical formula	C₁₃H₁₅NO₄S₂
Molar mass	313.3925 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Rentiapril is an ACE inhibitor.^[1]

References

↑ Takase K, Ikuse T, Aono H, Okahara A (January 1995). "Toxicity study of the angiotensin converting enzyme inhibitor rentiapril in rats". Arzneimittelforschung 45 (1): 15–8. PMID 7893262.

Antihypertensives: agents acting on the renin–angiotensin system (C09)

ACE inhibitors ("-pril")	Sulfhydryl-containing: Captopril Rentiapril Zofenopril Dicarboxylate-containing: Enalapril^# Benazepril Cilazapril Delapril Imidapril Lisinopril (+HCT) Moexipril Perindopril Quinapril (+HCT) Ramipril Spirapril Temocapril Trandolapril Phosphonate-containing: Fosinopril (+HCT) Other/ungrouped: Alacepril

AIIRAs/ ("-sartan")	Azilsartan Candesartan Eprosartan Fimasartan Irbesartan Losartan (+HCT) Olmesartan (+amlodipine) Tasosartan^§ Telmisartan (+HCT) Valsartan (+HCT, +amlodipine, +sacubitril)

Renin inhibitors/ ("-kiren")	Aliskiren (+amlodipine, +amlodipine and HCT) Remikiren^§

^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

This article is issued from Wikipedia - version of the Monday, December 14, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.