SNAPC2

Small nuclear RNA activating complex, polypeptide 2, 45kDa
Identifiers
Symbols	SNAPC2 ; PTFDELTA; SNAP45
External IDs	OMIM: 605076 MGI: 1914861 HomoloGene: 2318 GeneCards: SNAPC2 Gene
Gene ontology Molecular function • transcription factor activity, sequence-specific DNA binding Cellular component • nucleus • nucleoplasm • cytoplasm Biological process • regulation of transcription, DNA-templated • transcription from RNA polymerase II promoter • transcription from RNA polymerase III promoter • snRNA transcription • gene expression Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6618	102209
Ensembl	ENSG00000104976	ENSMUSG00000011837
UniProt	Q13487	Q91XA5
RefSeq (mRNA)	NM_003083	NM_133968
RefSeq (protein)	NP_003074	NP_598729
Location (UCSC)	Chr 19: 7.92 – 7.92 Mb	Chr 8: 4.25 – 4.26 Mb
PubMed search

snRNA-activating protein complex subunit 2 is a protein that in humans is encoded by the SNAPC2 gene.^[1][2]

Interactions

SNAPC2 has been shown to interact with SNAPC4.^[3][4]

References

1. Sadowski CL, Henry RW, Kobayashi R, Hernandez N (July 1996). "The SNAP45 subunit of the small nuclear RNA (snRNA) activating protein complex is required for RNA polymerase II and III snRNA gene transcription and interacts with the TATA box binding protein". Proc Natl Acad Sci U S A 93 (9): 4289–93. doi:10.1073/pnas.93.9.4289. PMC 39528. PMID 8633057.
2. "Entrez Gene: SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa".
3. Wong, M W; Henry R W; Ma B; Kobayashi R; Klages N; Matthias P; Strubin M; Hernandez N (January 1998). "The Large Subunit of Basal Transcription Factor SNAPc Is a Myb Domain Protein That Interacts with Oct-1". Mol. Cell. Biol. (UNITED STATES) 18 (1): 368–77. ISSN 0270-7306. PMC 121507. PMID 9418884.
4. Ma, B; Hernandez N (February 2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc". J. Biol. Chem. (United States) 276 (7): 5027–35. doi:10.1074/jbc.M009301200. ISSN 0021-9258. PMID 11056176.

Further reading

• Henry RW, Sadowski CL, Kobayashi R, Hernandez N (1995). "A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III". Nature 374 (6523): 653–6. doi:10.1038/374653a0. PMID 7715707.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Yoon JB, Roeder RG (1996). "Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein". Mol. Cell. Biol. Advances in Molecular and Cell Biology 16 (1): 1–9. doi:10.1016/S1569-2558(08)60061-2. ISBN 978-0-7623-0143-0. PMC 230972. PMID 8524284.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Wong MW, Henry RW, Ma B, et al. (1998). "The Large Subunit of Basal Transcription Factor SNAPc Is a Myb Domain Protein That Interacts with Oct-1". Mol. Cell. Biol. 18 (1): 368–77. PMC 121507. PMID 9418884.
• Ma B, Hernandez N (2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc". J. Biol. Chem. 276 (7): 5027–35. doi:10.1074/jbc.M009301200. PMID 11056176.
• Acierno JS, Kennedy JC, Falardeau JL, et al. (2001). "A physical and transcript map of the MCOLN1 gene region on human chromosome 19p13.3-p13.2". Genomics 73 (2): 203–10. doi:10.1006/geno.2001.6526. PMID 11318610.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Hinkley CS, Hirsch HA, Gu L, et al. (2003). "The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition". J. Biol. Chem. 278 (20): 18649–57. doi:10.1074/jbc.M204247200. PMID 12621023.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.