Thermospermine synthase

Thermospermine synthase
Identifiers
EC number 2.5.1.79
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Thermospermine synthase (EC 2.5.1.79, TSPMS, ACL5, SAC51) is an enzyme with systematic name S-adenosylmethioninamine:spermidine 3-aminopropyltransferase (thermospermine synthesizing).[1][2][3] This enzyme catalyses the following chemical reaction

S-adenosylmethioninamine + spermidine \rightleftharpoons S-methyl-5'-thioadenosine + thermospermine + H+

This enzyme is required for correct xylem specification through regulation of the lifetime of the xylem elements.

References

  1. Romer, P., Faltermeier, A., Mertins, V., Gedrange, T., Mai, R. and Proff, P. (2008). "Investigations about N-aminopropyl transferases probably involved in biomineralization". J. Physiol. Pharmacol. 59 Suppl 5: 27–37. PMID 19075322.
  2. Knott, J.M., Romer, P. and Sumper, M. (2007). "Putative spermine synthases from Thalassiosira pseudonana and Arabidopsis thaliana synthesize thermospermine rather than spermine". FEBS Lett. 581 (16): 3081–3086. doi:10.1016/j.febslet.2007.05.074. PMID 17560575.
  3. Muniz, L., Minguet, E.G., Singh, S.K., Pesquet, E., Vera-Sirera, F., Moreau-Courtois, C.L., Carbonell, J., Blazquez, M.A. and Tuominen, H. (2008). "ACAULIS5 controls Arabidopsis xylem specification through the prevention of premature cell death". Development 135 (15): 2573–2582. doi:10.1242/dev.019349. PMID 18599510.

External links

This article is issued from Wikipedia - version of the Thursday, March 31, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.