Tioxolone

Tioxolone
Names

IUPAC name 6-hydroxy-1,3-benzoxathiol-2-one
Identifiers
CAS Number	4991-65-5^N
ChEMBL	ChEMBL442687^N
ChemSpider	65113^N
EC Number	225-653-0
Jmol interactive 3D	Image
KEGG	D07211^Y
PubChem	72139
RTECS number	DM2953750
UNII	S0FAJ1R9CD^N
InChI InChI=1S/C7H4O3S/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3,8H^N Key: SLYPOVJCSQHITR-UHFFFAOYSA-N^N InChI=1/C7H4O3S/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3,8H Key: SLYPOVJCSQHITR-UHFFFAOYAC
SMILES C1=CC2=C(C=C1O)OC(=O)S2
Properties
Chemical formula	C₇H₄O₃S
Molar mass	168.16986
Melting point	158 to 160 °C (316 to 320 °F; 431 to 433 K)
Pharmacology
ATC code	D10AB03
Hazards
R-phrases	R22, R36/37/38
S-phrases	S26
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Tioxolone (INN, also spelled thioxolone) is an anti-acne preparation.^[1]

References

↑ Lius, V.; Sennerfeldt, P. (1979). "Local treatment of acne with tioxolone". Lakartidningen 76 (1–2): 39–41. PMID 153995.

Acne-treating agents (D10)

Antibacterial	Azelaic acid Benzoyl peroxide^# 8-Hydroxyquinoline Blue light therapy Tea tree oil

Keratolytic	Glycolic acid Salicylic acid^# Sulfur Benzoyl peroxide^#

Anti-inflammatory	Nicotinamide Ibuprofen # Aspirin # Red light therapy

Antibiotics	Clindamycin Dapsone Erythromycin Sulfacetamide Tetracyclines (Lymecycline Minocycline Doxycycline)

Hormonal	Antiandrogens Contraceptives

Retinoids	Adapalene Isotretinoin Motretinide Tazarotene Tretinoin

Other	Benzamycin Epristeride Mesulfen Pelretin Stridex Tioxolone

Combinations	Adapalene/benzoyl peroxide Benzoyl peroxide/clindamycin Clindamycin/tretinoin Erythromycin/isotretinoin Sulfacetamide/sulfur

^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

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