Tolimidone

Tolimidone
Systematic (IUPAC) name

5-(3-methylphenoxy)pyrimidin-2(1H)-one
Identifiers
CAS Number	41964-07-2
PubChem	CID 39065
ChemSpider	35751
UNII	MU3JD8E9IS^Y
KEGG	D06182
ChEMBL	CHEMBL8030
Chemical data
Formula	C₁₁H₁₀N₂O₂
Molar mass	202.21 g/mol
SMILES O=C2/N=C\C(\Oc1cc(ccc1)C)=C/N2

Tolimidole is a compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.

References

Lipinski, C. A.; Stam, J. G.; Pereira, J. N.; Ackerman, N. R.; Hess, H. J. (1980). "Bronchodilator and antiulcer phenoxypyrimidinones". Journal of Medicinal Chemistry 23 (9): 1026–31. doi:10.1021/jm00183a012. PMID 7411545.

Drugs for peptic ulcer and GERD/GORD (A02B)

H₂ antagonists ("-tidine")	Cimetidine Famotidine Lafutidine Lavoltidine (loxtidine) Niperotidine Nizatidine Ranitidine Roxatidine

Prostaglandins (E)/analogues ("-prost-")	Misoprostol Enprostil

Proton-pump inhibitors ("-prazole")	Dexlansoprazole Esomeprazole Ilaprazole Lansoprazole Omeprazole Pantoprazole Picoprazole Rabeprazole Tenatoprazole Timoprazole

Potassium-competitive acid blockers ("-prazan")	Linaprazan Revaprazan Soraprazan Vonoprazan

Other	Acetoxolone Alginic acid Arbaclofen placarbil Carbenoxolone Cetraxate Gefarnate Lesogaberan Pirenzepine Proglumide Rebamipide Sucralfate Sulglicotide Telenzepine Teprenone Troxipide Zolimidine

Combinations	Bismuth subcitrate/metronidazole/tetracycline

See also: Helicobacter pylori* eradication protocols*

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