TraJ 5' UTR

traJ 5' UTR
Predicted secondary structure and sequence conservation of traJ_5
Identifiers
Symbol traJ_5
Rfam RF00243
Other data
RNA type Cis-reg
Domain(s) Bacteria
SO 0000204

The traJ 5' UTR is a cis acting RNA element which is involved in regulating plasmid transfer in bacteria.

In conjugating bacteria the FinOP system regulates the transfer of F-like plasmids. The FinP gene encodes an antisense RNA product that is complementary to part of the 5' UTR of the traJ mRNA.[1] The traJ gene encodes a protein required for transcription from the major transfer promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from RNase E degradation.

References

  1. Arthur DC, Ghetu AF, Gubbins MJ, Edwards RA, Frost LS, Glover JN (2003). "FinO is an RNA chaperone that facilitates sense-antisense RNA interactions". EMBO J. 22 (23): 6346–55. doi:10.1093/emboj/cdg607. PMC 291848. PMID 14633993.

External links

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