Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific)

Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) (EC 2.5.1.89) is an enzyme with systematic name geranylgeranyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 7 isopentenyl units).^[1] This enzyme catalyses the following chemical reaction

geranylgeranyl diphosphate + 7 isopentenyl diphosphate

\rightleftharpoons

7 diphosphate + tritrans,heptacis-undecaprenyl diphosphate

This enzyme is involved in the biosynthesis of the glycosyl carrier lipid in some archaebacteria.

References

↑ Hemmi, H., Yamashita, S., Shimoyama, T., Nakayama, T. and Nishino, T. (2001). "Cloning, expression, and characterization of cis-polyprenyl diphosphate synthase from the thermoacidophilic archaeon Sulfolobus acidocaldarius". J. Bacteriol. 183 (1): 401–404. doi:10.1128/JB.183.1.401-404.2001. PMC 94892. PMID 11114943.

External links

Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) at the US National Library of Medicine Medical Subject Headings (MeSH)

Transferases: alkyl and aryl (EC 2.5)

2.5.1	Dimethylallyltranstransferase Thiaminase I Methionine adenosyltransferase Riboflavin synthase Dihydropteroate synthase Spermidine synthase Glutathione S-transferase Farnesyl-diphosphate farnesyltransferase Spermine synthase Alkylglycerone phosphate synthase Farnesyltransferase Geranylgeranyltransferase type 1 Porphobilinogen deaminase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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